| Autor: |
Cassidy LJ; Department of Gynaecology, Glasgow Royal Infirmary., Chudleigh A, Kennedy JH, Macnab JC |
| Jazyk: |
angličtina |
| Zdroj: |
British journal of obstetrics and gynaecology [Br J Obstet Gynaecol] 1988 Nov; Vol. 95 (11), pp. 1092-5. |
| DOI: |
10.1111/j.1471-0528.1988.tb06784.x |
| Abstrakt: |
A total of 143 consecutive patients with abnormal cervical cytology was examined at a large colposcopy clinic in Glasgow. Each patient had paired biopsies from normal and abnormal cervical epithelium examined both histologically and by immunoperoxidase staining for human papillomavirus (HPV) infection. More than 71% of the abnormal biopsies and 39% of the normal paired biopsies had histological evidence of HPV infection. Cytological evidence of HPV infection was seen in 38.5% of cervical smears. Immunocytochemistry revealed HPV antigen in 22% of the abnormal biopsies and in 4.2% of the 'normal' biopsies. The presence of HPV infection in colposcopically normal cervical tissue both inside and outside the transformation zone may help to explain why current methods for treatment of cervical HPV infection are often unsuccessful. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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