Iloprost Instillation in Two Neonates with Pulmonary Hypertension.

Autor:	Unal S; Department of Pediatrics, Division of Neonatology, Gazi University Hospital, Ankara, Turkey.; Department of Neonatology, Etlik Zubeyde Hanim Women's Health Teaching and Research Hospital, Ankara, Turkey., Aktas S; Department of Pediatrics, Division of Neonatology, Gazi University Hospital, Ankara, Turkey., Aksu M; Department of Pediatrics, Division of Neonatology, Gazi University Hospital, Ankara, Turkey., Hirfanoglu IM; Department of Pediatrics, Division of Neonatology, Gazi University Hospital, Ankara, Turkey., Atalay Y; Department of Pediatrics, Division of Neonatology, Gazi University Hospital, Ankara, Turkey., Turkyilmaz C; Department of Pediatrics, Division of Neonatology, Gazi University Hospital, Ankara, Turkey.
Jazyk:	angličtina
Zdroj:	Journal of the College of Physicians and Surgeons--Pakistan : JCPSP [J Coll Physicians Surg Pak] 2017 Apr; Vol. 27 (4), pp. 257-259.
Abstrakt:	Pulmonary hypertension may coexist with certain diseases in neonates. Iloprost inhalation is one of the treatments which cause selective pulmonary vasodilatation. Inhalation is not an easy way of drug administration in mechanically ventilated infants; as some exhibit desaturations during inhalation. Moreover, inhalation of drug requires cessation of mechanical ventilation, if patient is on high frequency oscillatory ventilation. We presented two patients with pulmonary hypertension; term baby with congenital diaphragmatic hernia and preterm baby with respiratory distress syndrome; who had iloprost instillation during mechanical ventilation treatment. Iloprost instillation was well tolerated with no side effects in the term patient with diaphragmatic hernia; whereas severe blood pressure fluctuations were observed in the preterm infant. This report may courage administration of iloprost in term neonates with resistant pulmonary hypertension.
Databáze:	MEDLINE
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