Liver resection for hepatocellular carcinoma ≥5 cm.

Autor:	Ettorre GM; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy., Levi Sandri GB; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy., Colasanti M; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy., Mascianà G; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy., de Werra E; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy., Santoro R; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy., Lepiane P; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy., Montalbano M; Hepatology and Infectious Diseases Unit, National Institute for Infectious Disease 'L. Spallanzani', Rome, Italy., Antonini M; Anesthesiology and Intensive Care Unit, National Institute for Infectious Disease 'L. Spallanzani', Rome, Italy., Vennarecci G; Division of General Surgery and Liver Transplantation, S. Camillo Hospital, Rome, Lazio, Italy.
Jazyk:	angličtina
Zdroj:	Translational gastroenterology and hepatology [Transl Gastroenterol Hepatol] 2017 Mar 24; Vol. 2, pp. 22. Date of Electronic Publication: 2017 Mar 24 (Print Publication: 2017).
DOI:	10.21037/tgh.2017.03.13
Abstrakt:	Background: Management of hepatocellular carcinoma (HCC) larger than 5 cm is still debated. The aim of our study was to compare morbidity and mortality after the surgical resection of HCC according to the nodule size. Methods: Since 2001, 429 liver resections for HCC were performed in our institution. We divided the cohort into two groups, 88 patients in group 1 patients with HCC diameter from 5 to 10 cm and 39 patients in group 2 with HCC diameter ≥10 cm. Results: In 30.7% of cases in the first group and in 35.9% of cases in the second group the HCC grew into a healthy liver. A major liver resection was performed in 36.3% of cases in group 1 vs. 66.6% in group 2 (P=0.001). In two cases for the first group and in ten cases in the second group a laparoscopic approach was performed. Median operative time was higher in group 2 (P=0.001). The median post-operative hospital stay was similar in the two groups (P=0.897). The post-operative morbidity was not different between the two groups (P=0.595). Conclusions: The tumour size does not contraindicate a surgical resection of HCC even in patient with HCC ≥10 cm. Competing Interests: Conflicts of Interest: The authors have no conflicts of interest to declare.
Databáze:	MEDLINE
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