New Macrolide-Lincosamide-Streptogramin B Resistance Gene erm (48) on the Novel Plasmid pJW2311 in Staphylococcus xylosus.

Autor: Wipf JRK; Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland., Riley MC; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, USA., Kania SA; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, USA., Bemis DA; Department of Biomedical and Diagnostic Sciences, College of Veterinary Medicine, University of Tennessee, Knoxville, Tennessee, USA., Andreis S; Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland., Schwendener S; Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland., Perreten V; Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Bern, Switzerland vincent.perreten@vetsuisse.unibe.ch.
Jazyk: angličtina
Zdroj: Antimicrobial agents and chemotherapy [Antimicrob Agents Chemother] 2017 Jun 27; Vol. 61 (7). Date of Electronic Publication: 2017 Jun 27 (Print Publication: 2017).
DOI: 10.1128/AAC.00066-17
Abstrakt: Whole-genome sequencing of Staphylococcus xylosus strain JW2311 from bovine mastitis milk identified the novel 49.3-kb macrolide-lincosamide-streptogramin B (MLS B ) resistance plasmid pJW2311. It contained the macrolide resistance gene mph (C), the macrolide-streptogramin B resistance gene msr (A), and the new MLS B resistance gene erm (48) and could be transformed into Staphylococcus aureus by electroporation. Functionality of erm (48) was demonstrated by cloning and expression in S. aureus .
(Copyright © 2017 American Society for Microbiology.)
Databáze: MEDLINE
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