| Autor: |
Barinian SB, Oganesian SS, Eloian MA |
| Jazyk: |
ruština |
| Zdroj: |
Kosmicheskaia biologiia i aviakosmicheskaia meditsina [Kosm Biol Aviakosm Med] 1988 May-Jun; Vol. 22 (3), pp. 58-60. |
| Abstrakt: |
The treatment of an isolated myocardial strip with Ca2+-activated neutral muscle proteases reduced the contraction amplitude and the relaxation rate of the myocardium by 21.0 +/- 1.7% and 25.0 +/- 1.6%, respectively, and the tension development rate--by 13.0 +/- 1.0%. In the animals exposed to +5 Gz (for 25 min daily during 15 days) the inhibitory effect of neutral proteases on the contractile function of an isolated myocardial strip increased from 23.0 +/- 1.7% to 34.0 +/- 4.3%. The initial sensitivity of the contraction apparatus to proteases did not return to the baseline after 30 days of readaptation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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