Sensitivity to Antibiotics of Bacteria Exposed to Gamma Radiation Emitted from Hot Soils of the High Background Radiation Areas of Ramsar, Northern Iran.

Autor: Mortazavi SMJ; Department of Diagnostic Imaging, Fox Chase Cancer Center, 333 Cottman Ave, Philadelphia, PA 19111, USA. mmortazavi@sums.ac.ir.; Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, Iran., Zarei S; Department of Microbiology and Parasitology, Faculty of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran., Taheri M; Department of Microbiology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran., Tajbakhsh S; Department of Microbiology and Parasitology, Faculty of Medicine, Bushehr University of Medical Sciences, Bushehr, Iran.; The Persian Gulf Tropical Medicine Research Center, Bushehr University of Medical Sciences, Bushehr, Iran., Mortazavi SA; Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, Iran., Ranjbar S; Medical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Momeni F; Medical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Masoomi S; Medical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Ansari L; Medical Physics Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Movahedi MM; Medical Physics and Medical Engineering Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran., Taeb S; Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, Iran., Zarei S; Varastegan University of Medical Sciences, Shiraz, Iran., Haghani M; Ionizing and Non-ionizing Radiation Protection Research Center (INIRPRC), Shiraz University of Medical Sciences, Shiraz, Iran.
Jazyk: angličtina
Zdroj: The international journal of occupational and environmental medicine [Int J Occup Environ Med] 2017 Apr; Vol. 8 (2), pp. 80-84.
DOI: 10.15171/ijoem.2017.958
Abstrakt: Background: Over the past several years our laboratories have investigated different aspects of the challenging issue of the alterations in bacterial susceptibility to antibiotics induced by physical stresses.
Objective: To explore the bacterial susceptibility to antibiotics in samples of Salmonella enterica subsp. enterica serovar Typhimurium ( S. typhimurium ), Staphylococcus aureus , and Klebsiella pneumoniae after exposure to gamma radiation emitted from the soil samples taken from the high background radiation areas of Ramsar, northern Iran.
Methods: Standard Kirby-Bauer test, which evaluates the size of the zone of inhibition as an indicator of the susceptibility of different bacteria to antibiotics, was used in this study.
Results: The maximum alteration of the diameter of inhibition zone was found for K. pneumoniae when tested for ciprofloxacin. In this case, the mean diameter of no growth zone in non-irradiated control samples of K. pneumoniae was 20.3 (SD 0.6) mm; it was 14.7 (SD 0.6) mm in irradiated samples. On the other hand, the minimum changes in the diameter of inhibition zone were found for S. typhimurium and S. aureus when these bacteria were tested for nitrofurantoin and cephalexin, respectively.
Conclusion: Gamma rays were capable of making significant alterations in bacterial susceptibility to antibiotics. It can be hypothesized that high levels of natural background radiation can induce adaptive phenomena that help microorganisms better cope with lethal effects of antibiotics.
Databáze: MEDLINE
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