Adrenoceptors in Dopaminergic Regulation of Rat Myocardial Contractility in Rats During Ontogeny.

Autor: Bilalova GA; Department of Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia. g.bilalova@mail.ru., Sitdikov FG; Department of Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia., Dikopol'skaya NB; Department of Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia., Shaikhelislamova MV; Department of Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia., Zefirov TL; Department of Human Health Protection, Kazan (Volga Region) Federal University, Kazan, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2017 Apr; Vol. 162 (6), pp. 769-772. Date of Electronic Publication: 2017 Apr 20.
DOI: 10.1007/s10517-017-3709-y
Abstrakt: The effects of different dopamine concentrations on contractility of myocardium with blocked α- or β-adrenoceptors were examined in vitro in 21- and 100-day old rats. In myocardial strips with blocked α-adrenoceptors, dopamine (10 -5 M) increased the right atrial contractile force. By contrast, this neurotransmitter (10 -9 -10 -5 M) reduced the contractile force of atrial and ventricular strips with blocked β-adrenoceptors.
Databáze: MEDLINE
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