Effect of Preparation Based on Trametes Pubescens Xylotroph Fungi on Lipid Peroxidation in the Blood of Experimental Animals under Conditions of Dark Stress.

Autor: Kolesnikova LI; Research Center for Family Health and Human Reproduction, Irkutsk, Russia., Kolesnikov SI; Research Center for Family Health and Human Reproduction, Irkutsk, Russia., Romanova ED; A. A. Ezhevsky Irkutsk State Agrarian University, Irkutsk, Russia., Chkhenkeli VA; A. A. Ezhevsky Irkutsk State Agrarian University, Irkutsk, Russia., Darenskaya MA; Research Center for Family Health and Human Reproduction, Irkutsk, Russia. marina_darenskaya@inbox.ru., Grebenkina LA; Research Center for Family Health and Human Reproduction, Irkutsk, Russia., Korytov LI; Research Center for Family Health and Human Reproduction, Irkutsk, Russia., Bugun OV; Research Center for Family Health and Human Reproduction, Irkutsk, Russia., Koroleva NV; Research Center for Family Health and Human Reproduction, Irkutsk, Russia., Gutnik IN; Irkutsk State University, Irkutsk, Russia., Antonenko FF; Russian X-Radiology Research Center, the Ministry of Health of the Russian Federation, Moscow, Russia.
Jazyk: angličtina
Zdroj: Bulletin of experimental biology and medicine [Bull Exp Biol Med] 2017 Apr; Vol. 162 (6), pp. 762-764. Date of Electronic Publication: 2017 Apr 20.
DOI: 10.1007/s10517-017-3707-0
Abstrakt: Using the model of dark stress caused by animal maintenance at dimmed light we showed that Trametin (product obtained during liquid-phase culturing of Trametes pubescens xylotroph fungi) effectively prevented oxidative stress under conditions of light deprivation. The preparation increased the level of unsaturation of lipids, reduced the concentration of primary and end-products of LPO, and increases both the integral parameter of the antioxidant defense system (total antioxidant activity) and its components (activity of superoxide dismutase and reduced glutathione).
Databáze: MEDLINE