Evaluation of the reliability of the Cutaneous Dermatomyositis Disease Area and Severity Index and the Cutaneous Assessment Tool-Binary Method in juvenile dermatomyositis among paediatric dermatologists, rheumatologists and neurologists.

Autor: Tiao J; Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, U.S.A.; Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, U.S.A., Feng R; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania, Philadelphia, PA, U.S.A., Berger EM; Hackensack University Medical Center, Hackensack, NJ, U.S.A., Brandsema JF; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A., Coughlin CC; Division of Dermatology, Washington University School of Medicine, St Louis, MO, U.S.A., Khan N; Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, U.S.A.; Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, U.S.A., Kichula EA; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A., Lerman MA; Division of Rheumatology, Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A., Lvovich S; St Christopher's Hospital for Children, Philadelphia, PA, U.S.A., McMahon PJ; Division of Dermatology, Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A., Rider LG; Environmental Autoimmunity Group. Clinical Research Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Bethesda, MD, U.S.A., Rubin AI; Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, U.S.A.; Division of Dermatology, Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A., Scalzi LV; Penn State Children's Hospital, Hershey, PA, U.S.A., Smith DM; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A., Taxter AJ; Brenner Children's Hospital, Wake Forest Baptist Medical Center, Winston-Salem, NC, U.S.A., Treat JR; Division of Dermatology, Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A., Williams RP; Minneapolis Clinic of Neurology, Maple Grove, MN, U.S.A., Yum SW; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA, U.S.A., Okawa J; Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, U.S.A., Werth VP; Department of Dermatology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, U.S.A.; Corporal Michael J. Crescenz Veterans Affairs Medical Center, Philadelphia, PA, U.S.A.
Jazyk: angličtina
Zdroj: The British journal of dermatology [Br J Dermatol] 2017 Oct; Vol. 177 (4), pp. 1086-1092. Date of Electronic Publication: 2017 Jul 31.
DOI: 10.1111/bjd.15596
Abstrakt: Background: The Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI) and Cutaneous Assessment Tool-Binary Method (CAT-BM) have been shown to be reliable and valid outcome measures to assess cutaneous disease in adult dermatomyositis (DM) and juvenile DM (JDM), respectively.
Objectives: This study compared the CDASI and CAT-BM for use by paediatric dermatologists, paediatric rheumatologists and paediatric neurologists in patients with JDM.
Methods: Five paediatric dermatologists, five paediatric rheumatologists and five paediatric neurologists each evaluated 14 patients with JDM using the CDASI, CAT-BM, and skin Physician Global Assessment (PGA) scales. Inter-rater reliability, intra-rater reliability, construct validity and completion time were compared.
Results: Inter-rater reliability for CDASI activity and damage scores was good to moderate for paediatric dermatologists and rheumatologists, but poor for paediatric neurologists. The inter-rater reliability for CAT-BM activity scores was moderate for paediatric dermatologists and rheumatologists, but poor for paediatric neurologists and poor across all specialties for damage scores. Intra-rater reliability for the CDASI and CAT-BM activity and damage scores was moderate to excellent for paediatric dermatologists, rheumatologists and neurologists. Strong associations were found between skin PGA activity and damage scores and CDASI or CAT-BM activity and damage scores, respectively (P < 0·002). The CDASI had a mean completion time of 5·4 min compared with that for the CAT-BM of 3·1 min.
Conclusions: Our data confirm the reliability of the CDASI activity and damage scores and the CAT-BM activity scores when used by paediatric dermatologists and rheumatologists in assessing JDM. Significant variation existed in the paediatric neurologists' scores.
(© 2017 British Association of Dermatologists.)
Databáze: MEDLINE
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