Regeneration of jejunal wall defect using an implant based on silk fibroin fibers.

Autor: Moisenovich MM; Biological Faculty, Moscow State University, Moscow, 119234, Russia. mmoisenovich@mail.ru., Kulikov DA; Vladimirskii Moscow Regional Research Clinical Institute, Moscow, 129110, Russia., Goncharenko AV; Biological Faculty, Moscow State University, Moscow, 119234, Russia., Arkhipova AY; Biological Faculty, Moscow State University, Moscow, 119234, Russia., Vasiljeva TV; Biological Faculty, Moscow State University, Moscow, 119234, Russia., Filyushkin YN; Vladimirskii Moscow Regional Research Clinical Institute, Moscow, 129110, Russia., Arkhipova LV; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290, Russia., Kotlyarova MS; Biological Faculty, Moscow State University, Moscow, 119234, Russia., Kulikov AV; Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino, Moscow oblast, 142290, Russia., Mashkov AE; Vladimirskii Moscow Regional Research Clinical Institute, Moscow, 129110, Russia., Agapov II; Shumakov Federal Research Center of Transplantation and Artificial Organs, Ministry of Healthcare of the Russian Federation, Moscow, 113182, Russia., Kirpichnikov MP; Biological Faculty, Moscow State University, Moscow, 119234, Russia.
Jazyk: angličtina
Zdroj: Doklady. Biochemistry and biophysics [Dokl Biochem Biophys] 2017 Jan; Vol. 472 (1), pp. 12-14. Date of Electronic Publication: 2017 Apr 19.
DOI: 10.1134/S1607672917010045
Abstrakt: Regenerative properties of fibroin implant vitalized with allogeneic bone marrow cells were assessed. The study was performed using the experimental model of rat jejunum wall damage. Three weeks after surgery, we observed recovery of all layers of the jejunum wall at the site of injury and complete degradation of the implant material.
Databáze: MEDLINE