Paediatric in-patient prescribing errors in Malaysia: a cross-sectional multicentre study.

Autor: Khoo TB; Department of Paediatrics, Institute of Paediatrics, Hospital Kuala Lumpur, Jalan Pahang, 50586, Kuala Lumpur, Malaysia. khootb@gmail.com., Tan JW; Paediatric Pharmacy Unit, Department of Pharmacy, Hospital Kuala Lumpur, Jalan Pahang, 50586, Kuala Lumpur, Malaysia., Ng HP; Department of Paediatrics, Sarawak General Hospital, Jalan Hospital, 93586, Kuching, Sarawak, Malaysia., Choo CM; Department of Paediatrics, Hospital Sultan Abdul Halim, Jalan Lencongan Timur, Bandar Amanjaya, 08000, Sungai Petani, Kedah, Malaysia., Bt Abdul Shukor INC; Department of Paediatrics, Hospital Segamat, Jalan Genuang, Bandar Putra, 85000, Segamat, Johor, Malaysia., Teh SH; Hospital Miri, Jalan Cahaya, 98000, Miri, Sarawak, Malaysia.
Jazyk: angličtina
Zdroj: International journal of clinical pharmacy [Int J Clin Pharm] 2017 Jun; Vol. 39 (3), pp. 551-559. Date of Electronic Publication: 2017 Apr 17.
DOI: 10.1007/s11096-017-0463-1
Abstrakt: Background There is a lack of large comprehensive studies in developing countries on paediatric in-patient prescribing errors in different settings. Objectives To determine the characteristics of in-patient prescribing errors among paediatric patients. Setting General paediatric wards, neonatal intensive care units and paediatric intensive care units in government hospitals in Malaysia. Methods This is a cross-sectional multicentre study involving 17 participating hospitals. Drug charts were reviewed in each ward to identify the prescribing errors. All prescribing errors identified were further assessed for their potential clinical consequences, likely causes and contributing factors. Main outcome measures Incidence, types, potential clinical consequences, causes and contributing factors of the prescribing errors. Results The overall prescribing error rate was 9.2% out of 17,889 prescribed medications. There was no significant difference in the prescribing error rates between different types of hospitals or wards. The use of electronic prescribing had a higher prescribing error rate than manual prescribing (16.9 vs 8.2%, p < 0.05). Twenty eight (1.7%) prescribing errors were deemed to have serious potential clinical consequences and 2 (0.1%) were judged to be potentially fatal. Most of the errors were attributed to human factors, i.e. performance or knowledge deficit. The most common contributing factors were due to lack of supervision or of knowledge. Conclusions Although electronic prescribing may potentially improve safety, it may conversely cause prescribing errors due to suboptimal interfaces and cumbersome work processes. Junior doctors need specific training in paediatric prescribing and close supervision to reduce prescribing errors in paediatric in-patients.
Databáze: MEDLINE