Antimicrobial resistance in the Bacteroides fragilis group in faecal microbiota from healthy Danish children.
Autor: | Sydenham TV; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark. Electronic address: Thomas.sydenham@dadlnet.dk., Jensen BH; Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark., Petersen AM; Department of Clinical Microbiology, Hvidovre University Hospital, Copenhagen, Denmark; Department of Gastroenterology, Hvidovre University Hospital, Copenhagen, Denmark., Krogfelt KA; Department of Microbiology and Infection Control, Statens Serum Institut, Copenhagen, Denmark., Justesen US; Department of Clinical Microbiology, Odense University Hospital, Odense, Denmark. |
---|---|
Jazyk: | angličtina |
Zdroj: | International journal of antimicrobial agents [Int J Antimicrob Agents] 2017 May; Vol. 49 (5), pp. 573-578. Date of Electronic Publication: 2017 Mar 31. |
DOI: | 10.1016/j.ijantimicag.2017.01.011 |
Abstrakt: | The Bacteroides fragilis group constitute a significant portion of the human gut microbiota and comprise a major proportion of anaerobic bacteria isolated in human infections. We established a baseline of antimicrobial susceptibility rates in the B. fragilis group in the intestinal tract of relatively antibiotic-naive healthy Danish children. From 174 faecal samples collected from children attending day care, 359 non-duplicate isolates were screened for antimicrobial susceptibility. Of these, 0.0%, 1.9%, 5.0% and 21.2% of isolates were intermediate-susceptible or resistant to metronidazole, meropenem, piperacillin/tazobactam and clindamycin, respectively. Eighteen additional studies reporting susceptibility rates in the B. fragilis group bacteria were identified by conducting a literature search. Heterogeneity among results from studies of B. fragilis group antimicrobial susceptibility rates in faecal microbiota exists. (Copyright © 2017 Elsevier B.V. and International Society of Chemotherapy. All rights reserved.) |
Databáze: | MEDLINE |
Externí odkaz: |