[Gardner-Diamond syndrome in a young man: A case report and literature review].

Autor: Henneton P; Centre de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France; Médecine interne et médecine vasculaire, hôpital Saint-Éloi, CHRU de Montpellier, 34295 Montpellier cedex 5, France., Frank M; Centre de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France., Litvinova E; Laboratoire d'immunologie, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France., Miranda S; Centre de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France., Messas E; Centre de référence des maladies vasculaires rares, hôpital européen Georges-Pompidou, AP-HP, 75908 Paris cedex 15, France., Darnige L; Service d'hématologie biologique, hôpital européen Georges-Pompidou, AP-HP, 20, rue Leblanc, 75908 Paris cedex 15, France. Electronic address: luc.darnige@aphp.fr.
Jazyk: francouzština
Zdroj: La Revue de medecine interne [Rev Med Interne] 2017 Sep; Vol. 38 (9), pp. 623-627. Date of Electronic Publication: 2017 Mar 28.
DOI: 10.1016/j.revmed.2017.01.008
Abstrakt: Introduction: Gardner-Diamond syndrome is a rare condition secondary to a sensitization to self-erythrocytes. It is predominantly seen in women and presents as a painful ecchymotic disorder. An underlying psychiatric disease or a triggering psychological stress is of important diagnostic value.
Case Report: We report a 24-year-old patient who presented with intermittent spontaneous painful ecchymosis since 5 years. Complementary investigations failed to identify an organic disorder. Gardner-Diamond syndrome was retained because of the clinical presentation, the negativity of diagnostic work-up and the identification of a psychological trauma. Patient management (pain, psychological support) is difficult, justifying a multidisciplinary approach.
Conclusion: Gardner-Diamond syndrome is a rare and unrecognized disorder, which should be discussed in the presence of ecchymotic or purpuric lesions that do not have a diagnostic orientation. Early recognition of this disorder enables initiation of an appropriate management, but also limits unnecessary additional explorations.
(Copyright © 2017 Société Nationale Française de Médecine Interne (SNFMI). Published by Elsevier SAS. All rights reserved.)
Databáze: MEDLINE
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