Circulating MicroRNAs as Potential Biomarkers of Atrial Fibrillation.
| Autor: | da Silva AM; Department of Clinical and Toxicologic Analyses, Federal University of Rio Grande do Norte, Natal, RN, Brazil., de Araújo JN; Department of Clinical and Toxicologic Analyses, Federal University of Rio Grande do Norte, Natal, RN, Brazil., de Freitas RC; Department of Clinical and Toxicologic Analyses, Federal University of Rio Grande do Norte, Natal, RN, Brazil., Silbiger VN; Department of Clinical and Toxicologic Analyses, Federal University of Rio Grande do Norte, Natal, RN, Brazil. |
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| Jazyk: | angličtina |
| Zdroj: | BioMed research international [Biomed Res Int] 2017; Vol. 2017, pp. 7804763. Date of Electronic Publication: 2017 Mar 02. |
| DOI: | 10.1155/2017/7804763 |
| Abstrakt: | Atrial fibrillation (AF) is the most common supraventricular arrhythmia in the population. MicroRNAs (small endogenous noncoding RNAs) are attractive candidates as biomarkers for AF, especially considering that miRNAs are stable and are detected within easily accessible biofluids such as blood. In this review, we selected twelve studies (2012 to 2016) that were classified according to the sample type. We aimed to provide an overview of the role of circulating miRNAs in AF and to discuss the variability of the results, seeking to improve the perspective of the use of miRNAs as potential noninvasive biomarkers for this heart disease. Competing Interests: The authors declare that there is no conflict of interests regarding the publication of this paper. |
| Databáze: | MEDLINE |
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