Clostridium baratii : a rare case of pneumonia associated with an Alzheimer patient in Rio de Janeiro, Brazil.

Autor:	Lima CO; Hospital de Clínicas Rio Mar Barra LTDA , Avenida Candido Portinari, 555. Rio de Janeiro, RJ , Brazil., da Rocha VM; Hospital Universitário Gaffrée e Guinle , Rua Mariz e Barros, 755. Rio de Janeiro, RJ , Brazil., Ferreira EO; Universidade Federal do Rio de Janeiro, Laboratory of Anaerobes Biology, Avenida Carlos Chagas Filho, 373, Bloco I-2. Rio de Janeiro, RJ, Brazil; Universidade Federal do Rio de Janeiro, Polo Xerém, Estrada de Xerém, 27. Duque de Caxias, RJ, Brazil., Filho JS; Universidade Federal do Rio de Janeiro, Laboratory of Anaerobes Biology , Avenida Carlos Chagas Filho, 373, Bloco I-2. Rio de Janeiro, RJ , Brazil., Serradas LR; Hospital de Clínicas Rio Mar Barra LTDA , Avenida Candido Portinari, 555. Rio de Janeiro, RJ , Brazil., Silva RO; Universidade Federal de Minas Gerais, Veterinary School , Avenida Antônio Carlos, 6627. Belo Horizonte, MG , Brazil., Lobato FC; Universidade Federal de Minas Gerais, Veterinary School , Avenida Antônio Carlos, 6627. Belo Horizonte, MG , Brazil., Domingues RM; Universidade Federal do Rio de Janeiro, Laboratory of Anaerobes Biology , Avenida Carlos Chagas Filho, 373, Bloco I-2. Rio de Janeiro, RJ , Brazil.
Jazyk:	angličtina
Zdroj:	JMM case reports [JMM Case Rep] 2016 Aug 30; Vol. 3 (4), pp. e005041. Date of Electronic Publication: 2016 Aug 30 (Print Publication: 2016).
DOI:	10.1099/jmmcr.0.005041
Abstrakt:	Introduction: Clostridium baratii is rarely associated with human diseases. Infection is usuallcaused by ingestion of contaminated food, and infant botulism is the most common clinical presentation. Case Report: Here we report a case of pneumonia by a non-toxigenic strain of C. baratii in an Alzheimer 70-year-old male with sepsis in Rio de Janeiro, Brazil. The micro-organism was identified by phenotypical tests, mass spectrometry (MALDI-TOF), DNA amplification (PCR) and sequencing of the 16S rRNA gene. Testing for the presence of botulinum F toxin was made using multiplex PCR. Bioassay for a large number of colonies was performed in mice to evaluate the production of any lethal toxin, but the results were negative. Conclusion: To our knowledge, there are no cases of C. baratii infection reported in Brazil and we highlight the importance of anaerobic lab tests in the standard routine of diagnosis.
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu