Optical and electrochemical dual channel sensing of Cu 2+ using functionalized furo[2,3-d]pyrimidines-2,4[1H,3H]-diones.

Autor: Kumar M; Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee 247667, India., Kumawat LK; Department of Applied Chemistry, University of Johannesburg, Johannesburg, South Africa., Bhatt P; Department of Chemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh 530045, India., Jha A; Department of Chemistry, GITAM Institute of Science, GITAM University, Visakhapatnam, Andhra Pradesh 530045, India., Agarwal S; Department of Applied Chemistry, University of Johannesburg, Johannesburg, South Africa., Sharma A; Department of Chemistry, Indian Institute of Technology Roorkee, Roorkee 247667, India. Electronic address: anujsfcy@iitr.ac.in., Gupta VK; Department of Applied Chemistry, University of Johannesburg, Johannesburg, South Africa. Electronic address: vinodg@uj.ac.za.
Jazyk: angličtina
Zdroj: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy [Spectrochim Acta A Mol Biomol Spectrosc] 2017 Jun 15; Vol. 181, pp. 73-81. Date of Electronic Publication: 2017 Mar 18.
DOI: 10.1016/j.saa.2017.03.034
Abstrakt: Owing to their easy accessibility and high degree of structural and functional diversity, many multicomponent reactions (MCRs) have been a rich source of conjugate π-systems, functionalised chromophores (or fluorophore) and redox active molecules. Despite their high explorative potential and practical benefits, only a few MCR products have been so far investigated for their metal sensing abilities. In the present report, two furopyrimidinones (FPys) based molecular systems have been synthesized by [4+1] cycloaddition based MCR sequence. Designed chemosensors displayed optic (absorption spectra) as well as electroanalytical (ion selective electrode) response toward Cu 2+ ion in solution and membrane phase respectively (dual channel sensing). Different aspects of both the sensing phenomena such as selectivity, association constants, detection limit, membrane composition etc. were studied in detail using UV-Vis spectroscopy, NMR titration and cell assembly. Both the compounds showed excellent performance characteristics such as high selectivity, acceptable affinity and low detection limits (10 -7 M) in both sensing assays with potential utility in the area of sample monitoring.
(Copyright © 2017 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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