BRIDG: a domain information model for translational and clinical protocol-driven research.

Autor:	Becnel LB; Clinical Data Interchange Standards Consortium, Austin, TX, USA.; Dan L. Duncan Cancer Center, Baylor College of Medicine, Houston, TX, USA., Hastak S; Samvit Solutions LLC, Reston, VA, USA., Ver Hoef W; Samvit Solutions LLC, Reston, VA, USA., Milius RP; National Marrow Donor Program, Minneapolis, MN, USA., Slack M; Food and Drug Administration Office of Strategic Programs, Silver Spring, MD, USA., Wold D; Clinical Data Interchange Standards Consortium, Austin, TX, USA., Glickman ML; Computer Network Architects Inc. and ISO/TC 215 Health Informatics, Rockville, MD, USA., Brodsky B; Food and Drug Administration Office of Strategic Programs, Silver Spring, MD, USA., Jaffe C; HL7 (Health Level 7 International), Ann Arbor, MI, USA., Kush R; Clinical Data Interchange Standards Consortium, Austin, TX, USA., Helton E; National Cancer Institute, Rockville, MD, USA.
Jazyk:	angličtina
Zdroj:	Journal of the American Medical Informatics Association : JAMIA [J Am Med Inform Assoc] 2017 Sep 01; Vol. 24 (5), pp. 882-890.
DOI:	10.1093/jamia/ocx004
Abstrakt:	Background: It is critical to integrate and analyze data from biological, translational, and clinical studies with data from health systems; however, electronic artifacts are stored in thousands of disparate systems that are often unable to readily exchange data. Objective: To facilitate meaningful data exchange, a model that presents a common understanding of biomedical research concepts and their relationships with health care semantics is required. The Biomedical Research Integrated Domain Group (BRIDG) domain information model fulfills this need. Software systems created from BRIDG have shared meaning "baked in," enabling interoperability among disparate systems. For nearly 10 years, the Clinical Data Standards Interchange Consortium, the National Cancer Institute, the US Food and Drug Administration, and Health Level 7 International have been key stakeholders in developing BRIDG. Methods: BRIDG is an open-source Unified Modeling Language-class model developed through use cases and harmonization with other models. Results: With its 4+ releases, BRIDG includes clinical and now translational research concepts in its Common, Protocol Representation, Study Conduct, Adverse Events, Regulatory, Statistical Analysis, Experiment, Biospecimen, and Molecular Biology subdomains. Interpretation: The model is a Clinical Data Standards Interchange Consortium, Health Level 7 International, and International Standards Organization standard that has been utilized in national and international standards-based software development projects. It will continue to mature and evolve in the areas of clinical imaging, pathology, ontology, and vocabulary support. BRIDG 4.1.1 and prior releases are freely available at https://bridgmodel.nci.nih.gov . (© The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu