Video-assisted thoracic surgery lobectomy does not offer any functional recovery advantage in comparison to the open approach 3 months after the operation: a case matched analysis†.

Autor:	Salati M; Unit of Thoracic Surgery, AOU Ospedali Ruiniti, Ancona, Italy., Brunelli A; Department of Thoracic Surgery, St. Jame's University Hospital, Leeds, UK., Xiumè F; Unit of Thoracic Surgery, AOU Ospedali Ruiniti, Ancona, Italy., Monteverde M; Unit of Thoracic Surgery, AOU Ospedali Ruiniti, Ancona, Italy., Sabbatini A; Unit of Thoracic Surgery, AOU Ospedali Ruiniti, Ancona, Italy., Tiberi M; Unit of Thoracic Surgery, AOU Ospedali Ruiniti, Ancona, Italy., Pompili C; Department of Thoracic Surgery, St. Jame's University Hospital, Leeds, UK., Palloni R; t33 company Srl, Ancona, Italy., Refai M; Unit of Thoracic Surgery, AOU Ospedali Ruiniti, Ancona, Italy.
Jazyk:	angličtina
Zdroj:	European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery [Eur J Cardiothorac Surg] 2017 Jun 01; Vol. 51 (6), pp. 1177-1182.
DOI:	10.1093/ejcts/ezx013
Abstrakt:	Objectives: The objective of the present study was to compare functional loss [forced expiratory volume in one second to forced vital capacity ratio (FEV1), DLCO and VO2max reduction] after VATS versus open lobectomies. Methods: We performed a prospective observational study on 195 patients who had a pulmonary lobectomy from June 2010 to November 2014 and who were able to complete a 3-months functional evaluation follow-up program. Since the VATS technique was our first choice for performing lobectomies from January 2012, we divided the patients into two groups: the OPEN group (112 patients) and the VATS group (83 patients). The open approach was intended as a muscle sparing/nerve sparing lateral thoracotomy. Fourteen baseline factors were used to construct a propensity score to match the VATS-group patients with their OPEN-group counterparts. These two matched groups were then compared in terms of reduction of FEV1, DLCO and VO2max (Mann-Whitney test). Results: The propensity score analysis yielded 83 well-matched pairs of OPEN and VATS patients. In both groups, 3 months postoperatively, we found a reduction in FEV1, DLCO and VO2max values (OPEN patients: FEV1-10%, DLCO -11.9%, VO2max - 5.5%; VATS patients: FEV1-7.2%, DLCO-10.6%, VO2max-6.9%). The reductions in FEV1, DLCO and VO2max were similar to those in the two matched groups, with a Cohen effect size <0.2 for all the comparisons. Conclusions: In 3 months, both OPEN patients and VATS patients experienced a reduction in their preoperative functional parameters. VATS lobectomy does not offer any advantages in terms of FEV1, DLCO and exercise capacity recovery in comparison to the muscle-sparing thoracotomy approach. (© The Author 2017. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. All rights reserved.)
Databáze:	MEDLINE
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