Feline platynosomiasis: analysis of the association of infection levels with pathological and biochemical findings.

Autor: Ramos DG; Unidade Acadêmica Especial de Ciências Agrárias, Universidade Federal de Goiás - UFG, Jataí, GO, Brasil.; Instituto de Ciências Agrárias, Centro Universitário de Mineiros - UNIFIMES, Mineiros, GO, Brasil., Santos AR; Faculdade de Medicina Veterinária, Universidade Federal de Mato Grosso - UFMT, Cuiabá, MT, Brasil., Freitas LD; Faculdade de Medicina Veterinária, Universidade Federal de Mato Grosso - UFMT, Cuiabá, MT, Brasil., Braga ÍA; Instituto de Ciências Agrárias, Centro Universitário de Mineiros - UNIFIMES, Mineiros, GO, Brasil., Silva EP; Faculdade de Medicina Veterinária, Universidade Federal de Mato Grosso - UFMT, Cuiabá, MT, Brasil., Soares LM; Faculdade de Medicina Veterinária, Universidade Federal de Mato Grosso - UFMT, Cuiabá, MT, Brasil., Antoniassi NA; Instituto de Ciências da Saúde, Universidade Federal de Mato Grosso - UFMT, Sinop, MT, Brasil., Furlan FH; Faculdade de Medicina Veterinária, Universidade Federal de Mato Grosso - UFMT, Cuiabá, MT, Brasil., Pacheco RC; Faculdade de Medicina Veterinária, Universidade Federal de Mato Grosso - UFMT, Cuiabá, MT, Brasil.
Jazyk: angličtina
Zdroj: Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria [Rev Bras Parasitol Vet] 2017 Jan-Mar; Vol. 26 (1), pp. 54-59. Date of Electronic Publication: 2017 Mar 16.
DOI: 10.1590/S1984-29612017009
Abstrakt: Platynosomiasis is a common feline hepatic disease caused by Platynosomum fastosum (Trematoda - Dicrocoelidae), which is also known as 'lizard poisoning'. Most reports of feline platynosomiasis show that this disease is sporadic and manifests with uncommon lesions; its pathogenicity is still not well understood. This study aimed to describe liver injuries and enzymatic changes associated with natural P. fastosum infection in 47 stray cats in an endemic area. Overall, 38.3% (18/47) of cats were parasitized, and 2,358 flukes (P. fastosum) were collected (131 - mean intensity of parasitism; 50.2 - mean abundance). The alanine transaminase (ALT) measure was significantly higher in parasitized animals, while alkaline phosphatase (ALP) showed no statistical difference between parasitized and non-parasitized animals. In infected animals, gross pathological lesions and microscopic liver injuries ranged from mild to severe, and were similar to those in previous descriptions of feline platynosomiasis. Nonetheless, the intensity of parasitism was not related to the severity of macroscopic or microscopic hepatic injuries. However, feline platynosomiasis should be considered in the differential diagnosis of feline liver disorders, as well as, in any program of helminth control, even if no clinical abnormalities are present.
Databáze: MEDLINE