Prevalence and Prognostic Features of ECG Abnormalities in Acute Stroke: Findings From the SIREN Study Among Africans.

Autor:	Adeoye AM; University of Ibadan, Ibadan, Nigeria., Ogah OS; University of Ibadan, Ibadan, Nigeria., Ovbiagele B; Medical University of South Carolina, Charleston, SC, USA., Akinyemi R; Federal Medical Centre, Abeokuta, Nigeria., Shidali V; Ahmadu Bello University, Zaria, Nigeria., Agyekum F; University of Ghana Medical School, Accra, Ghana., Aje A; University of Ibadan, Ibadan, Nigeria., Adebayo O; University of Ibadan, Ibadan, Nigeria., Akinyemi JO; University of Ibadan, Ibadan, Nigeria., Kolo P; University of Ilorin Teaching Hospital, Ilorin, Nigeria., Appiah LT; Komfo Anokye Teaching Hospital, Kumasi, Ghana., Iheonye H; Ahmadu Bello University, Zaria, Nigeria., Kelechukwu U; Federal Medical Center, Umuahia, Nigeria., Ganiyu A; Jos University Teaching Hospital, Jos, Nigeria., Olunuga TO; Federal Medical Centre, Abeokuta, Nigeria., Akpa O; University of Ibadan, Ibadan, Nigeria., Olagoke OO; University of Ibadan, Ibadan, Nigeria., Sarfo FS; Komfo Anokye Teaching Hospital, Kumasi, Ghana., Wahab K; University of Ilorin Teaching Hospital, Ilorin, Nigeria., Olowookere S; University of Ilorin Teaching Hospital, Ilorin, Nigeria., Fakunle A; University of Ibadan, Ibadan, Nigeria., Akpalu A; University of Ghana Medical School, Accra, Ghana., Adebayo PB; Ladoke Akintola University of Technology, Ogbomoso, Nigeria., Nkromah K; University of Ghana Medical School, Accra, Ghana., Yaria J; University of Ibadan, Ibadan, Nigeria., Ibinaiye P; Ahmadu Bello University, Zaria, Nigeria., Ogbole G; University of Ibadan, Ibadan, Nigeria., Olumayowa A; Sacred Heart Hospital, Abeokuta, Nigeria., Lakoh S; University of Ibadan, Ibadan, Nigeria., Calys-Tagoe B; University of Ghana Medical School, Accra, Ghana., Olowoyo P; Federal University Teaching Hospital, Ido-Ekiti, Nigeria., Innocent C; Federal Medical Center, Umuahia, Nigeria., Tiwari HK; University of Alabama at Birmingham, Birmingham, AL, USA., Arnett D; University of Kentucky at Lexington, Lexington, KY, USA., Godwin O; Jos University Teaching Hospital, Jos, Nigeria., Ayotunde B; University of Ibadan, Ibadan, Nigeria., Akpalu J; University of Ghana Medical School, Accra, Ghana., Obiora O; Federal Medical Center, Umuahia, Nigeria., Joseph O; University of Ibadan, Ibadan, Nigeria., Omisore A; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria., Jenkins C; Jos University Teaching Hospital, Jos, Nigeria., Lackland D; Medical University of South Carolina, Charleston, SC, USA., Owolabi L; Aminu Kano Teaching Hospital, Kano, Nigeria., Isah S; Aminu Kano Teaching Hospital, Kano, Nigeria., Dambatta AH; Aminu Kano Teaching Hospital, Kano, Nigeria., Komolafe M; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria., Bock-Oruma A; Delta State University Teaching Hospital, Ogara, Nigeria., Melikam ES; University of Ibadan, Ibadan, Nigeria., Imoh LC; Federal Medical Center, Umuahia, Nigeria., Sunmonu T; Federal Medical Centre, Owo, Nigeria., Gebregziabher M; Medical University of South Carolina, Charleston, SC, USA., Olabisi O; Obafemi Awolowo University Teaching Hospital, Ile-Ife, Nigeria., Armstrong K; Medical University of South Carolina, Charleston, SC, USA., Onyeonoro UU; Federal Medical Center, Umuahia, Nigeria., Sanya E; University of Ilorin Teaching Hospital, Ilorin, Nigeria., Agunloye AM; University of Ibadan, Ibadan, Nigeria., Ogunjimi L; University of Ibadan, Ibadan, Nigeria., Arulogun O; University of Ibadan, Ibadan, Nigeria., Farombi TH; University of Ibadan, Ibadan, Nigeria., Obiabo O; Delta State University Teaching Hospital, Ogara, Nigeria., Obiako R; Ahmadu Bello University, Zaria, Nigeria., Owolabi M; University of Ibadan, Ibadan, Nigeria. Electronic address: mayowaowolabi@yahoo.com.
Jazyk:	angličtina
Zdroj:	Global heart [Glob Heart] 2017 Jun; Vol. 12 (2), pp. 99-105. Date of Electronic Publication: 2017 Mar 14.
DOI:	10.1016/j.gheart.2017.01.002
Abstrakt:	Background: Africa has a growing burden of stroke with associated high morbidity and a 3-year fatality rate of 84%. Cardiac disease contributes to stroke occurrence and outcomes, but the precise relationship of abnormalities as noted on a cheap and widely available test, the electrocardiogram (ECG), and acute stroke outcomes have not been previously characterized in Africans. Objectives: The study assessed the prevalence and prognoses of various ECG abnormalities among African acute stroke patients encountered in a multisite, cross-national epidemiologic study. Methods: We included 890 patients from Nigeria and Ghana with acute stroke who had 12-lead ECG recording within first 24 h of admission and stroke classified based on brain computed tomography scan or magnetic resonance imaging. Stroke severity at baseline was assessed using the Stroke Levity Scale (SLS), whereas 1-month outcome was assessed using the modified Rankin Scale (mRS). Results: Patients' mean age was 58.4 ± 13.4 years, 490 were men (55%) and 400 were women (45%), 65.5% had ischemic stroke, and 85.4% had at least 1 ECG abnormality. Women were significantly more likely to have atrial fibrillation, or left ventricular hypertrophy with or without strain pattern. Compared to ischemic stroke patients, hemorrhagic stroke patients were less likely to have atrial fibrillation (1.0% vs. 6.7%; p = 0.002), but more likely to have left ventricular hypertrophy (64.4% vs. 51.4%; p = 0.004). Odds of severe disability or death at 1 month were higher with severe stroke (AOR: 2.25; 95% confidence interval: 1.44 to 3.50), or atrial enlargement (AOR: 1.45; 95% confidence interval: 1.04 to 2.02). Conclusions: About 4 in 5 acute stroke patients in this African cohort had evidence of a baseline ECG abnormality, but presence of any atrial enlargement was the only independent ECG predictor of death or disability. (Copyright © 2017 World Heart Federation (Geneva). All rights reserved.)
Databáze:	MEDLINE
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