Vancomycin-associated linear IgA disease mimicking toxic epidermal necrolysis.

Autor: Pereira AR; Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil., Moura LH; Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil., Pinheiro JR; Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil., Pasin VP; Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil., Enokihara MM; Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil., Porro AM; Universidade Federal de São Paulo (Unifesp) - São Paulo (SP), Brazil.
Jazyk: angličtina
Zdroj: Anais brasileiros de dermatologia [An Bras Dermatol] 2016 Sep-Oct; Vol. 91 (5 suppl 1), pp. 35-38.
DOI: 10.1590/abd1806-4841.20164665
Abstrakt: Linear IgA dermatosis is a rare subepidermal autoimmune blistering disease characterized by linear deposition of IgA along the basement membrane zone. In the last three decades, many different drugs have been associated with the drug-induced form of the disease, especially vancomycin. We report a case of vancomycin-induced linear IgA disease mimicking toxic epidermal necrolysis. The aim of this work is to emphasize the need to include this differential diagnosis in cases of epidermal detachment and to review the literature on the subject and this specific clinical presentation.
Databáze: MEDLINE