Linear IgA and IgG bullous dermatosis.

Autor: Fernandes KA; Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil., Galvis KH; Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil., Gomes AC; Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil., Nogueira OM; Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil., Felix PA; Hospital Naval Marcílio Dias (HNMD) - Rio de Janeiro (RJ), Brazil.; Hospital Federal dos Servidores do Estado (HFSE) - Rio de Janeiro (RJ), Brazil., Vargas TJ; Hospital Federal de Bonsucesso (HFB) -Rio de Janeiro (RJ), Brazil.
Jazyk: angličtina
Zdroj: Anais brasileiros de dermatologia [An Bras Dermatol] 2016 Sep-Oct; Vol. 91 (5 suppl 1), pp. 32-34.
DOI: 10.1590/abd1806-4841.20164630
Abstrakt: Childhood linear immunoglobulin A dermatosis is a rare autoimmune vesiculobullous disease. It results in linear deposition of autoantibodies (immunoglobulin A) against antigens in the basal membrane zone, leading to subepidermal cleavage. Additional depositions of immunoglobulin G and complement-3 might occur. It is still debated whether concomitant findings of immunoglobulins A and G should be considered a subtype of this dermatosis or a new entity. Further studies are needed to recognize this clinical variant.
Databáze: MEDLINE