Attenuation of Cardiovascular Response to Direct Laryngoscopy and Intubation, Comparative Study of Lignocaine, Nifedipine, and Placebo During General Anesthesia.
| Autor: | Manne VS; Department of Anaesthesia, NRI Medical College and Hospital, Guntur, Andhra Pradesh, India., Paluvadi VR; Department of Anaesthesia, NRI Medical College and Hospital, Guntur, Andhra Pradesh, India. |
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| Jazyk: | angličtina |
| Zdroj: | Anesthesia, essays and researches [Anesth Essays Res] 2017 Jan-Mar; Vol. 11 (1), pp. 47-51. |
| DOI: | 10.4103/0259-1162.200227 |
| Abstrakt: | Background/objective: The purpose of the study was to compare the attenuation of cardiovascular response to direct laryngoscopy and intubation using lignocaine, nifedipine, and placebo during general anesthesia. Materials and Methods: This prospective study was done in sixty patients undergoing noncardiac surgeries of American Society of Anesthesiologists health status Class I and II between the age groups of 18-60 years. They were randomly divided into three groups of 20 each (lignocaine group, nifedipine group, and placebo group) and cardiovascular response (heart rate [HR] and blood pressure [BP]) to direct laryngoscopy and intubation were compared. Results: The rise in HR and BP was most significant in the placebo group and insignificant in lignocaine and nifedipine groups. Conclusion: Nifedipine is effective than lignocaine in attenuating hypertensive response, and lignocaine is effective in attenuating rate pressure product than nifedipine. Competing Interests: There are no conflicts of interest. |
| Databáze: | MEDLINE |
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