k-t accelerated aortic 4D flow MRI in under two minutes: Feasibility and impact of resolution, k-space sampling patterns, and respiratory navigator gating on hemodynamic measurements.

Autor: Bollache E; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Barker AJ; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Dolan RS; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Carr JC; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., van Ooij P; Department of Radiology, Academic Medical Center, Amsterdam, the Netherlands., Ahmadian R; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Powell A; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Collins JD; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA., Geiger J; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Diagnostic and Interventional Radiology, University Hospital of Würzburg, Würzburg, Germany., Markl M; Department of Radiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.; Department of Biomedical Engineering, McCormick School of Engineering, Northwestern University, Chicago, Illinois, USA.
Jazyk: angličtina
Zdroj: Magnetic resonance in medicine [Magn Reson Med] 2018 Jan; Vol. 79 (1), pp. 195-207. Date of Electronic Publication: 2017 Mar 07.
DOI: 10.1002/mrm.26661
Abstrakt: Purpose: To assess the performance of highly accelerated free-breathing aortic four-dimensional (4D) flow MRI acquired in under 2 minutes compared to conventional respiratory gated 4D flow.
Methods: Eight k-t accelerated nongated 4D flow MRI (parallel MRI with extended and averaged generalized autocalibrating partially parallel acquisition kernels [PEAK GRAPPA], R = 5, TRes = 67.2 ms) using four k y -k z Cartesian sampling patterns (linear, center-out, out-center-out, random) and two spatial resolutions (SRes1 = 3.5 × 2.3 × 2.6 mm 3 , SRes2 = 4.5 × 2.3 × 2.6 mm 3 ) were compared in vitro (aortic coarctation flow phantom) and in 10 healthy volunteers, to conventional 4D flow (16 mm-navigator acceptance window; R = 2; TRes = 39.2 ms; SRes = 3.2 × 2.3 × 2.4 mm 3 ). The best k-t accelerated approach was further assessed in 10 patients with aortic disease.
Results: The k-t accelerated in vitro aortic peak flow (Qmax), net flow (Qnet), and peak velocity (Vmax) were lower than conventional 4D flow indices by ≤4.7%, ≤ 11%, and ≤22%, respectively. In vivo k-t accelerated acquisitions were significantly shorter but showed a trend to lower image quality compared to conventional 4D flow. Hemodynamic indices for linear and out-center-out k-space samplings were in agreement with conventional 4D flow (Qmax ≤ 13%, Qnet ≤ 13%, Vmax ≤ 17%, P > 0.05).
Conclusion: Aortic 4D flow MRI in under 2 minutes is feasible with moderate underestimation of flow indices. Differences in k-space sampling patterns suggest an opportunity to mitigate image artifacts by an optimal trade-off between scan time, acceleration, and k-space sampling. Magn Reson Med 79:195-207, 2018. © 2018 International Society for Magnetic Resonance in Medicine.
(© 2017 International Society for Magnetic Resonance in Medicine.)
Databáze: MEDLINE
Externí odkaz: