| Autor: |
Kuan YC; Sarawak General Hospital, Department of Medicine, 93586 Kuching, Sarawak, Malaysia. kychien2006@yahoo.com., Nurain MN; Putrajaya Hospital, Department of Medicine, Endocrine Unit, Malaysia. |
| Jazyk: |
angličtina |
| Zdroj: |
The Medical journal of Malaysia [Med J Malaysia] 2017 Feb; Vol. 72 (1), pp. 50-52. |
| Abstrakt: |
Described herein, a case of Langerhans cell histiocytosis (LCH) in an adult with Idiopathic Thrombocytopenic Purpura (ITP) diagnosed at age ten. She presented with cranial diabetes insipidus, later developed hypogonadotrophic hypogonadism and multiple cervical lympadenopathy from which histopathology of excisional biopsy confirmed LCH. Magnetic resonance imaging showed thickened pituitary stalk. Association of ITP and LCH is unknown but the question of LCH presenting as isolated thrombocytopenia in childhood only to be discovered in adulthood when there was pituitary and bone involvement remains. It reemphasizes the need for high index of suspicion and the challenges in diagnosing LCH at the outset. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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