[The role of the modification of cyclic purine nucleotide molecule in the regulation of platelet acid glycosidase activity].

Autor: Petrovich IuA, Trusova NF
Jazyk: ruština
Zdroj: Voprosy meditsinskoi khimii [Vopr Med Khim] 1987 Sep-Oct; Vol. 33 (5), pp. 102-5.
Abstrakt: 3'5'-cGMP activated beta-glucuronidase, beta-galactosidase, beta-glucosidase and N-acetyl-beta-glucosaminidase in blood platelets, while 2'3'-cGMP, 3,5'-cGMP, N2O2'-dipalmitoyl and 5'-GMP did not affect the activity of these glycosidases. The guanylate cyclase system appears to be involved in activation of blood platelets glycosidases since it is well known that 3'5'-cGMP activates the thrombocyte protein kinase.
Databáze: MEDLINE