[Causes of death among prostate cancer patients of different ages].

Autor: Dariy EV; The European Medical Center, Moscow.
Jazyk: ruština
Zdroj: Urologiia (Moscow, Russia : 1999) [Urologiia] 2016 Feb (1), pp. 62-68.
Abstrakt: To date, there is no unified approach to evaluating and treating patients with suspected prostate cancer taking into account their age and comorbidities. That was the rationale for conducting this study.
Aim: To assess the clinical course of prostate cancer in men of all ages with comorbidities.
Materials and Methods: The study included 408 patients aged 50 to 92 years (mean age 74.3 years) with histologically verified prostate cancer. 30 (7.4%) patients had stage T1 disease, 273 (66.9%) - T2, 91 (22.3%) - T3 and 14 (3.4%) - T4. The maximum follow-up was 22 years, the minimum one - 6 months (on average 15.4 years).
Results: During the follow-up 159 patients died (39%), 51 of them (32%) of prostate cancer, 108 (68%) - from other diseases. Among the latter the causes of death were cancer (20.4%), cardiovascular and bronchopulmonary diseases (79.6%). Cancer-specific survival rate was 41.4 +/-12,4%, the survival rate for other diseases 23.4 +/-10,6% (p<0.05).
Conclusion: We need a differentiated approach to selecting treatment for patients with prostate cancer, especially of old age, including the option for active surveillance of patients with clinically insignificant prostate cancer.
Databáze: MEDLINE