Position statement of the Brazilian Academy of Rhinology on the use of antihistamines, antileukotrienes, and oral corticosteroids in the treatment of inflammatory sinonasal diseases.

Autor:	Mion OG; Universidade de São Paulo (USP), Disciplina de Otorrinolaringologia, São Paulo, SP, Brazil. Electronic address: ominon@uol.com.br., Mello JF Jr; Universidade de São Paulo (USP), Faculdade de Medicina, São Paulo, SP, Brazil., Dutra DL; Universidade de São Paulo (USP), Faculdade de Medicina, Departamento de Otorrinolaringologia, São Paulo, SP, Brazil., Andrade NA; Universidade de São Paulo (USP), Faculdade de Medicina, Departamento de Otorrinolaringologia, São Paulo, SP, Brazil., Almeida WL; Universidade de São Paulo (USP), Faculdade de Medicina, Departamento de Otorrinolaringologia, São Paulo, SP, Brazil., Anselmo-Lima WT; Universidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto, Departamento de Otorrinolaringologia, Ribeirão Preto, SP, Brazil., Filho LL; Universidade Federal de São Paulo (UNIFESP), Ciências da Saúde, São Paulo, SP, Brazil., Carvalho E Castro J; Universidade Federal de São Paulo (UNIFESP), Otorrinolaringologia, São Paulo, SP, Brazil., Guimarães RE; Universidade Federal de Minas Gerais (UFMG), Faculdade de Medicina, Belo Horizonte, MG, Brazil; Universidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto, Ribeirão Preto, SP, Brazil., Lessa MM; Universidade Federal da Bahia (UFBA), Faculdade de Medicina, Disciplina de Otorrinolaringologia, Salvador, BA, Brazil., Maniglia SF; Hospital Instituto Paranaense de Otorrinolaringologia, Centro de Rinite e Alergia, Curitiba, PR, Brazil., Meireles RC; Universidade do Estado do Rio de Janeiro (UERJ), Rio de Janeiro, RJ, Brazil., Nakanishi M; Universidade de São Paulo (USP), Disciplina de Otorrinolaringologia, São Paulo, SP, Brazil; Universidade de Brasília (UnB), Faculdade de Medicina, Brasília, DF, Brazil., Pignatari SS; Universidade Federal de São Paulo (UNIFESP), Departamento de Otorrinolaringologia e Cabeça e Pescoço, São Paulo, SP, Brazil., Roithmann R; Universidade Luterana do Brasil (ULBRA), Faculdade de Medicina, Otorrinolaringologia, Canoas, RS, Brazil; Mount Sinai Hospital, Department of Othorhinolaryngology, Toronto, Canada., Romano FR; Universidade de São Paulo (USP), Faculdade de Medicina, Ciências, São Paulo, SP, Brazil., Santos RP; Universidade Federal de São Paulo (UNIFESP), Otorrinolaringologia, São Paulo, SP, Brazil., Santos MC; Universidade de São Paulo (USP), Faculdade de Medicina, Departamento de Otorrinolaringologia, São Paulo, SP, Brazil., Tamashiro E; Universidade de São Paulo (USP), Faculdade de Medicina de Ribeirão Preto, Departamento de Oftalmologia, Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, Ribeirão Preto, SP, Brazil.
Jazyk:	angličtina
Zdroj:	Brazilian journal of otorhinolaryngology [Braz J Otorhinolaryngol] 2017 Mar - Apr; Vol. 83 (2), pp. 215-227. Date of Electronic Publication: 2017 Jan 21.
DOI:	10.1016/j.bjorl.2017.01.002
Abstrakt:	Introduction: Inflammatory conditions of the nose and paranasal sinuses are very prevalent in the general population, resulting in marked loss of quality of life in affected patients, as well as significant work, leisure, and social activity losses. These patients require specific and specialized treatment. A wide range of oral medications are available. Objective: The present document is aimed to clarify, for professionals treating patients with inflammatory sinonasal diseases, both specialists and general practitioners, specific oral therapies in noninfectious nasal inflammatory conditions. Methods: The methodology used to create this article included the search for the key words: oral corticosteroids, antihistamines, antileukotrienes, rhinitis, rhinosinusitis in the MEDLINE and EMBASE databases in the last 5 years. Since no relevant article was found for the text on the subject of interest in the last 5 years, the search was extended for another 5 years, and so on, according to the authors' needs. Results: Relevant literature was found regarding the use of antihistamines, antileukotrienes and oral corticosteroids in these conditions. The Brazilian Academy of Rhinology emphasizes, after extensive discussion by the collegiate, key points in the treatment with these drugs. Conclusion: There is support in the literature for the use of these drugs; however, final considerations about the role of each of them have been made. (Copyright © 2017. Published by Elsevier Editora Ltda.)
Databáze:	MEDLINE
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