Age and sex related differences in normal pituitary gland and fossa volumes.

Autor:	Pecina HI; Department of Radiology, University Hospital Center \'Sestre Milosrdnice\', Zagreb, Croatia., Pecina TC; Department of Radiology, University Hospital, Dubrava, Zagreb, Croatia., Vyroubal V; Antropological Centre, Croatian Academy of Sciences and Arts, Zagreb, Croatia., Kruljac I; Department of Endocrinology, Diabetes and Metabolic Diseases, Mladen Sekso, University Hospital Center, Sestre Milosrdnice, University of Zagreb Medical School, Zagreb, Croatia., Slaus M; Anthropological Center, Croatian Academy of Sciences and Arts, Ante Kovacica 5, Zagreb 10000, Croatia, mario.slaus@zg.t-com.hr.
Jazyk:	angličtina
Zdroj:	Frontiers in bioscience (Elite edition) [Front Biosci (Elite Ed)] 2017 Mar 01; Vol. 9 (2), pp. 204-213. Date of Electronic Publication: 2017 Mar 01.
DOI:	10.2741/e796
Abstrakt:	This study investigates the influence of age and sex on the volumes of the pituitary fossa and gland in 91 males and 108 females from Croatia who underwent magnetic resonance imaging of the endocranium for complaints not related to the pituitary gland. Isometric 3DT1 MPRAGE and 3DT1 MPR sequences were obtained on 1.5. Tesla and analysed on ISSA software. The volumes were obtained from the sum of all the areas multiplied by the thickness of the section. The mean volume of the pituitary fossa for males was 1111.1.4 mm 3 , for females 1354.4.2 mm 3 . Correlation analysis showed a significant negative correlation (P=0.0.09) between age of the patient, and pituitary volume. Age of the patient and free volume demonstrate a significant positive correlation (P=0.0.01) indicating that the amount of unoccupied space in the pituitary fossa significantly increases with age. Determining general morphological values, as well as variations of pituitary depth and the occupation of the fossa with the pituitary gland is of great help in everyday diagnostic and therapeutic approach.
Databáze:	MEDLINE
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