Negative Pressure Induced Droplet Generation in a Microfluidic Flow-Focusing Device.

Autor: Teo AJT; Queensland Micro- and Nanotechnology Centre, Griffith University , 170 Kessels Road QLD 4111, Brisbane, Australia.; School of Mechanical and Aerospace Engineering, Nanyang Technological University , 50 Nanyang Avenue, Singapore (639798)., Li KH; School of Mechanical and Aerospace Engineering, Nanyang Technological University , 50 Nanyang Avenue, Singapore (639798)., Nguyen NT; Queensland Micro- and Nanotechnology Centre, Griffith University , 170 Kessels Road QLD 4111, Brisbane, Australia., Guo W; Queensland Micro- and Nanotechnology Centre, Griffith University , 170 Kessels Road QLD 4111, Brisbane, Australia.; School of Aeronautics, Northwestern Polytechnical University , 127 West Youyi Rd, Xi'an, Shaanxi China., Heere N; Queensland Micro- and Nanotechnology Centre, Griffith University , 170 Kessels Road QLD 4111, Brisbane, Australia.; Institute of Cognitive Science, University of Osnabrück , 49069 Osnabrück, Germany., Xi HD; School of Aeronautics, Northwestern Polytechnical University , 127 West Youyi Rd, Xi'an, Shaanxi China., Tsao CW; Department of Mechanical Engineering, National Central University , No. 300, Zhongda Road, Taoyuan, Taiwan., Li W; School of Mechanical, Materials and Mechatronic Engineering, University of Wollongong , Wollongong, NSW 2522, Australia., Tan SH; Queensland Micro- and Nanotechnology Centre, Griffith University , 170 Kessels Road QLD 4111, Brisbane, Australia.
Jazyk: angličtina
Zdroj: Analytical chemistry [Anal Chem] 2017 Apr 18; Vol. 89 (8), pp. 4387-4391. Date of Electronic Publication: 2017 Feb 16.
DOI: 10.1021/acs.analchem.6b05053
Abstrakt: We introduce an effective method to actively induce droplet generation using negative pressure. Droplets can be generated on demand using a series of periodic negative pressure pulses. Fluidic network models were developed using the analogy to electric networks to relate the pressure conditions for different flow regimes. Experimental results show that the droplet volume is correlated to the pressure ratio with a power law of 1.3. Using a pulsed negative pressure at the outlet, we are able to produce droplets in demand and with a volume proportional to the pulse width.
Databáze: MEDLINE