Relationship between clinical evaluation and ultrasound assessment of rheumatoid arthritis patients using a 12 joint score.

Autor: Cerqueira M; Rheumatology department, Hospital Conde de Bertiandos, ULSAM, Ponte de Lima, Portugal., Teixeira F; Rheumatology department, Hospital Conde de Bertiandos, ULSAM, Ponte de Lima, Portugal., Sousa Neves J; Rheumatology department, Hospital Conde de Bertiandos, ULSAM, Ponte de Lima, Portugal., Peixoto D; Rheumatology department, Hospital Conde de Bertiandos, ULSAM, Ponte de Lima, Portugal., Afonso MC; Rheumatology department, Hospital Conde de Bertiandos, ULSAM, Ponte de Lima, Portugal., Costa JA; Rheumatology department, Hospital Conde de Bertiandos, ULSAM, Ponte de Lima, Portugal.
Jazyk: angličtina
Zdroj: International journal of rheumatic diseases [Int J Rheum Dis] 2017 Jul; Vol. 20 (7), pp. 852-858. Date of Electronic Publication: 2017 Feb 09.
DOI: 10.1111/1756-185X.13005
Abstrakt: Aim: To identify if the use of a systematic ultrasound (US) evaluation has relevance in the determination of disease activity in rheumatoid arthritis patients on biological disease-modifying anti-rheumatic drug treatment.
Methods: A 12 joint US assessment was performed on the same day of the routine clinical examination. Both Grey-scale (GS) and Power Doppler (PD) were graded semi-quantitatively (0-3 scale).
Results: Forty-one patients were included. GS or PD > 0 were found in 24% and 3% of the ankles, 21% and 17% of the wrists, 19% and 9% of the second metacarpophalangeal joints (MCP), 7% and 2% of the third MCP, 6% and 0% of the knees and 5% and 0% of the elbows, respectively; tenosynovitis of the tibialis posterior was found in 19% of the ankles. Eight of the patients with Disease Activity Score of 28 joints (DAS28) ≤ 2.6 (n = 15) had an US score of 0. Twenty-seven joints (6.7%) had US evidence of synovitis but were not considered to be swollen; 10 (2.5%) were considered to be swollen but had no US evidence of synovitis.
Conclusions: Using a 12 joint US assessment, a high proportion of patients with DAS28 < 2.6 were found to have inflammatory US activity, and a significant proportion of patients had evidence of tenosynovitis of the tibialis posterior, which may be difficult to clinically detect. A regular and standardized US assessment of RA patients is therefore warranted to complement clinical evaluation and better define disease activity.
(© 2017 Asia Pacific League of Associations for Rheumatology and John Wiley & Sons Australia, Ltd.)
Databáze: MEDLINE
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