Evaluation of therapeutic laser influences on the healing of third-degree burns in rats according to different wavelengths.

Autor: Fekrazad R; a AJA University of Medical Sciences , Tehran , Iran., Nikkerdar A; b Private Practice , London , UK., Joharchi K; c Shahid Beheshti University , Tehran , Iran., Kalhori KA; c Shahid Beheshti University , Tehran , Iran., Mashhadi Abbas F; c Shahid Beheshti University , Tehran , Iran., Salimi Vahid F; d Private Practice , Tehran , Iran.
Jazyk: angličtina
Zdroj: Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology [J Cosmet Laser Ther] 2017 Aug; Vol. 19 (4), pp. 232-236. Date of Electronic Publication: 2017 Feb 06.
DOI: 10.1080/14764172.2017.1288255
Abstrakt: Introduction: One of the most important innovative methods for tissue repair promotion is therapeutic lasers with photobiomodulution effects. The aim of this study was to investigate the effect of four different wavelengths of therapeutic laser (405, 532, 660 and 810 nm) on healing of third-degree burns from both clinical and pathological standpoints in rats.
Materials and Methods: 60 male Wistar rats were used. Animals were anesthetized and dorsal hairs were shaved and third-degree skin burns were created by use of a 95°C copper stamp. Lesions were irradiated with 1.5 J/cm 2 energy densities and 200 mW/cm 2 power densities.
Results: Statistical analyses of the "wound contraction" changes between five groups during the study showed more reduction in wound size in all laser groups in comparison with the control group; but these differences were not statistically significant except between red and blue lasers on the last day of experiment.
Discussion: Results of our study showed that using therapeutic lasers with green, blue, red, and infrared wavelengths may accelerate healing process. This trend is more obvious in red and infrared groups especially after acute phase, however, this effect was neither statistically nor clinically significant.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje