[Severe pulmonary involvement in hypocomplementemic urticarial vasculitis (HUV)].
| Autor: | Raoufi M; Service de Pneumologie, Hôpital Militaire Mohamed V, Rabat, Maroc., Laine M; Service de Pneumologie, Hôpital Militaire Mohamed V, Rabat, Maroc., Amrani HN; Service de Pneumologie, Hôpital Militaire Mohamed V, Rabat, Maroc., Souhi H; Service de Pneumologie, Hôpital Militaire Mohamed V, Rabat, Maroc., Janah H; Service de Pneumologie, Hôpital Militaire Mohamed V, Rabat, Maroc., Elouazzani H; Service de Pneumologie, Hôpital Militaire Mohamed V, Rabat, Maroc., Rhorfi IA; Service de Pneumologie, Hôpital Militaire Mohamed V, Rabat, Maroc., Abid A; Service de Pneumologie, Hôpital Militaire Mohamed V, Rabat, Maroc. |
|---|---|
| Jazyk: | francouzština |
| Zdroj: | The Pan African medical journal [Pan Afr Med J] 2016 Jul 28; Vol. 24, pp. 285. Date of Electronic Publication: 2016 Jul 28 (Print Publication: 2016). |
| DOI: | 10.11604/pamj.2016.24.285.8168 |
| Abstrakt: | Pulmonary involvement in hypocomplementemic urticarial vasculitis (HUV) or Mac Duffie syndrome is extremely rare with a poor prognosis. We report the case of a 55-year-old female patient treated for HUV over a period of 20 years. The diagnosis was confirmed on the basis of urticarial lesions, ocular inflammation, positive C1q-p test by immunodiffusion, with low rate of C1q. The patient was treated with cycles of cyclophosphamide, corticoids and rituximab as she developed class III dyspnea (NYHA classification ). The clinico-radiological and functional assessment showed thoracic distension and severe obstructive pulmonary disease which found no significant improvement with systemic treatment Aerosol therapy was started and the patient had a marked clinical improvement. Pulmonary involvement in Mac Duffie hypocomplementemic urticarial vasculitis worsens the patient short-term vital prognosis. The knowledge of the different types of pulmonary involvement opens new therapeutic prospects. Competing Interests: Conflits d’intérêts Les auteurs ne déclarent aucun conflit d'intérêts. |
| Databáze: | MEDLINE |
| Externí odkaz: |
|