Thymoma masquerading as transfusion dependent anemia.

Autor: Muzamil J; Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Shiekh AA; Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Bhat GM; Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Lone AR; Department of Medical Oncology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Bhat S; Department of Clinical Hematology, Sher-I-Kashmir Institute of Medical Sciences, Srinagar, Jammu and Kashmir, India., Nabi F; Department of Prosthodonsia, Government Dental College, Srinagar, Jammu and Kashmir, India.
Jazyk: angličtina
Zdroj: Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology [Indian J Med Paediatr Oncol] 2016 Oct-Dec; Vol. 37 (4), pp. 296-299.
DOI: 10.4103/0971-5851.195729
Abstrakt: Pure red cell aplasia (PRCA) is a known entity in clinical medicine. Patients are often transfusion dependent for their whole life. Ascertaining its etiology is always a herculean task. We received a similar transfusion-dependent patient, who on evaluation was found to have thymoma as an etiological factor. Thymoma presenting as PRCA is seen in 2%-5% patients and evaluating PRCA for thymoma is seen in 5%-13% patient. As per the WHO histopathological classification, thymoma has six types and Type A is associated with PRCA and Type B is associated with myasthenia gravis. This correlation was not seen in our patient, who had Type B thymoma. Surgical resection of thymus improves 30% of PRCA and rest needs immunosuppression. Our patient was not the surgical candidate, and hence he was put on chemotherapy.
Competing Interests: There are no conflicts of interest.
Databáze: MEDLINE