Scar Remodeling with the Association of Monopolar Capacitive Radiofrequency, Electric Stimulation, and Negative Pressure.

Autor:	Nicoletti G; 1 Plastic and Reconstructive Surgery, Department of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia , Pavia, Italy .; 2 Advanced Technologies for Regenerative Medicine and Inductive Surgery Research Center, University of Pavia , Pavia, Italy .; 3 Plastic and Reconstructive Surgery Unit, Istituti Clinici Scientifici Maugeri , Pavia, Italy ., Perugini P; 4 Department of Drug Sciences, University of Pavia , Pavia, Italy ., Bellino S; 1 Plastic and Reconstructive Surgery, Department of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia , Pavia, Italy ., Capra P; 4 Department of Drug Sciences, University of Pavia , Pavia, Italy ., Malovini A; 5 Laboratory of Informatics and Systems Engineering for Clinical Research, Istituti Clinici Scientifici Maugeri , Pavia, Italy ., Jaber O; 6 Freelance Plastic Surgeon, San Martino Siccomario , Pavia, Italy ., Tresoldi M; 1 Plastic and Reconstructive Surgery, Department of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia , Pavia, Italy .; 3 Plastic and Reconstructive Surgery Unit, Istituti Clinici Scientifici Maugeri , Pavia, Italy ., Faga A; 1 Plastic and Reconstructive Surgery, Department of Clinical Surgical Diagnostic and Pediatric Sciences, University of Pavia , Pavia, Italy .; 2 Advanced Technologies for Regenerative Medicine and Inductive Surgery Research Center, University of Pavia , Pavia, Italy .; 3 Plastic and Reconstructive Surgery Unit, Istituti Clinici Scientifici Maugeri , Pavia, Italy .
Jazyk:	angličtina
Zdroj:	Photomedicine and laser surgery [Photomed Laser Surg] 2017 May; Vol. 35 (5), pp. 246-258. Date of Electronic Publication: 2017 Jan 24.
DOI:	10.1089/pho.2016.4180
Abstrakt:	Objective: A study was established to objectively assess the effects of low-intensity electromagnetic and electric stimulation plus negative pressure on mature scars. Background: Radiofrequency plus negative pressure therapy demonstrated a favorable reorganization and regeneration of the collagen and elastic fibers and was proposed for the treatment of cellulitis and skin stretch marks. Methods: Twenty-six mature scars in 20 Caucasian patients (15 females and 5 males) were enrolled in the study. The treatments were carried out with a Class I, BF-type electromedical device equipped with a radiofrequency generator, an electric pulse generator, and a vacuum pump twice a week for 3 months. Corneometry, transepidermal water loss, elastometry, colorimetry, and three-dimensional skin surface pattern were objectively assessed with Multi Probe Adapter System MPA and PRIMOS pico. A subjective assessment was carried out with the VAS and PSAS scales. Each scar was compared before and after the treatment and with the skin in the corresponding healthy contralateral anatomical area at the same times. Results: Reduction of the scar surface wrinkling and overall scar flattening were demonstrated after the treatment. The scar slightly tended to approach the color and elasticity of healthy skin too. Conclusions: The combined local treatment of mature scars with low-intensity electromagnetic and electric stimulation in association with negative pressure might suggest a favorable synergic effect on the scar collagen and elastic fiber remodeling.
Databáze:	MEDLINE
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