Chemical Composition and In Vitro Antioxidant, Cytotoxic, Antimicrobial, and Larvicidal Activities of the Essential Oil of Mentha piperita L. (Lamiaceae).

Autor: da Silva Ramos R; Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil., Rodrigues AB; Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil., Farias AL; Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil., Simões RC; Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil., Pinheiro MT; Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil., Ferreira RM; Laboratory of Arthropoda, Federal University of Amapá, Rodovia Juscelino Kubitschek, Km 02, Jardim Marco Zero, Macapá, AP, Brazil., Costa Barbosa LM; Laboratory of Arthropoda, Federal University of Amapá, Rodovia Juscelino Kubitschek, Km 02, Jardim Marco Zero, Macapá, AP, Brazil., Picanço Souto RN; Laboratory of Arthropoda, Federal University of Amapá, Rodovia Juscelino Kubitschek, Km 02, Jardim Marco Zero, Macapá, AP, Brazil., Fernandes JB; Department of Chemistry, Federal University of São Carlos, Washington Luis Highway, Km 235, SP-310, 13565-905 São Carlos, SP, Brazil., Santos LD; Laboratory of Chemistry, Federal University of Pará, Rua Augusto Corrêa, 01-Setor Básico, 66075-110 Belém, PA, Brazil., de Almeida SS; Laboratory of Pharmacognosy and Phytochemistry, Federal University of Amapá, Highway Juscelino Kubitschek, Km 02, Macapá, AP, Brazil.
Jazyk: angličtina
Zdroj: TheScientificWorldJournal [ScientificWorldJournal] 2017; Vol. 2017, pp. 4927214. Date of Electronic Publication: 2017 Jan 01.
DOI: 10.1155/2017/4927214
Abstrakt: The essential oil was obtained by hydrodistillation and the identification and quantification of components were achieved with the use of GC-MS analysis. The antioxidant activity was evaluated by the method of sequestration of DPPH. Essential oils were used for study the cytotoxic front larvae of Artemia salina . In the evaluation of the antimicrobial activity of essential oils, we employed the disk-diffusion method. The potential larvicide in mosquito larvae of the third stage of development of Aedes aegypti to different concentrations of essential oils was evaluated. The major compounds found in the essential oils of M. piperita were linalool (51.8%) and epoxyocimene (19.3%). The percentage of antioxidant activity was 79.9 ± 1.6%. The essential oil showed LC 50 = 414.6  μ g/mL front of A. saline and is considered highly toxic. It shows sensitivity and halos significant inhibition against E. coli . The essential possessed partial larvicidal efficiency against A. aegypti .
Competing Interests: The authors declare that they have no competing interests.
Databáze: MEDLINE
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