Central nervous system vasculitis in adults: An update.

Autor: Dutra LA; General Neurology Division, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil; Hospital Israelita Albert Einstein, São Paulo, Brazil., de Souza AW; Rheumatology Division, Universidade Federal de São Paulo, São Paulo, Brazil., Grinberg-Dias G; Hospital Israelita Albert Einstein, São Paulo, Brazil., Barsottini OG; General Neurology Division, Department of Neurology and Neurosurgery, Universidade Federal de São Paulo, São Paulo, Brazil., Appenzeller S; Rheumatology Division, Universidade Estadual de Campinas, Campinas, São Paulo, Brazil. Electronic address: appenzellersimone@gmail.com.
Jazyk: angličtina
Zdroj: Autoimmunity reviews [Autoimmun Rev] 2017 Feb; Vol. 16 (2), pp. 123-131. Date of Electronic Publication: 2017 Jan 11.
DOI: 10.1016/j.autrev.2016.12.001
Abstrakt: Primary central nervous system vasculitis (PCNSV) is a challenging diagnosis due to broad clinical manifestations and variable specificity and sensitivity of laboratory and imaging diagnostic tools. Differential diagnosis includes reversible cerebral vasoconstriction syndrome (RCVS), secondary vasculitis of the CNS and other noninflammatory vasculopathies. Brain biopsy is essential for definitive diagnosis and to exclude mimickers. Recent data show that data large-vessel PCNSV present worse prognosis when compared to small-vessel PCNSV. Herein we review diagnosis and management of PCNSV, secondary vasculitis of CNS and RCVS.
(Copyright © 2016. Published by Elsevier B.V.)
Databáze: MEDLINE
Externí odkaz: