Corneal Melt after Boston Keratoprosthesis: Clinical Presentation, Management, Outcomes and Risk Factor Analysis.

Autor: Bouhout S; a Faculty of Medicine, McGill University , Montréal , Québec , Canada., Robert MC; b Department of Ophthalmology , Centre Hospitalier de l'Université de Montréal , Montréal , Québec , Canada., Deli S; c Faculty of Medicine, Université de Montréal , Montréal , Québec , Canada., Harissi-Dagher M; b Department of Ophthalmology , Centre Hospitalier de l'Université de Montréal , Montréal , Québec , Canada.
Jazyk: angličtina
Zdroj: Ocular immunology and inflammation [Ocul Immunol Inflamm] 2018; Vol. 26 (5), pp. 693-699. Date of Electronic Publication: 2017 Jan 12.
DOI: 10.1080/09273948.2016.1269930
Abstrakt: Purpose: To determine the presentation, risk factors, and outcomes of keratolysis after Boston type I keratoprosthesis (B-KPro).
Methods: Retrospective chart review.
Results: A total of 16 (14%) of the 110 eyes (96 patients) which underwent B-KPro implantation developed keratolysis at an average 20 ± 11 months. Retroprosthetic membrane (RPM), infectious keratitis, and corneal dellen were identified in 31%, 25%, and 13% of corneal melts, respectively. Five eyes had keratolysis without a readily identifiable cause. RPM (odds-ratio, OR = 4.4, p = 0.02) and infectious keratitis (OR = 17.6, p<0.0005) were confirmed as significant risk factors. Retinal detachment (p = 0.001) and choroidal detachment (p = 0.003) were more common in eyes with keratolysis. Management included B-KPro removal or exchange (n = 7), amniotic membrane transplantation (n = 1), tectonic corneal transplantation (n = 2), medical treatment (n = 4), and observation (n = 2).
Conclusions: The risk of keratolysis following B-Kpro increases with the development of RPM and infectious keratitis. Patients with keratolysis had higher complication rates and should receive rigorous monitoring.
Databáze: MEDLINE
Externí odkaz:
Nepřihlášeným uživatelům se plný text nezobrazuje