| Autor: |
Ramkumar R; a Department of Biotechnology , Padmavani Arts and Science College for Women , Salem , India., Balasubramani G; b Department of Biotechnology , School of Biosciences, Periyar University , Salem , India., Raja RK; b Department of Biotechnology , School of Biosciences, Periyar University , Salem , India., Raja M; b Department of Biotechnology , School of Biosciences, Periyar University , Salem , India., Govindan R; c Department of Physics , School of Physical Sciences, Periyar University , Salem , India., Girija EK; c Department of Physics , School of Physical Sciences, Periyar University , Salem , India., Perumal P; b Department of Biotechnology , School of Biosciences, Periyar University , Salem , India. |
| Abstrakt: |
The Lantana camara Linn root extract derived gold nanoparticles (Au NPs) were characterized by Ultraviolet-Visible spectroscopy, X-ray diffraction, fourier transform-infrared, high resolution transmission electron microscopy, selected area electron diffraction pattern and energy dispersive X-ray analyses. In DPPH assay, the inhibitory concentration (IC 50 ) of Au NPs and gallic acid was 24.17 and 5.39 μg/ml, whereas, for cytotoxicity assay, the IC 50 of Au NPs was 17.72 and 32.98 μg/ml on MBA-MB-231 and Vero cells, respectively. Thus, the Au NPs possess significant in vitro antioxidant and cytotoxic properties which could be considered as potential alternate for the development of anticancer drug in future. |
