Nutrition assessment and its relationship with performance and Glasgow prognostic scores in Vietnamese patients with esophageal cancer.

Autor:	Quyen TC; Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand.; National Institute of Nutrition, Hanoi, Vietnam., Angkatavanich J; Department of Nutrition and Dietetics, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand. Email: jongjitan@gmail.com., Thuan TV; National Cancer Hospital, Hanoi, Vietnam., Xuan VV; National Cancer Hospital, Hanoi, Vietnam., Tuyen LD; National Institute of Nutrition, Hanoi, Vietnam., Tu DA; National Cancer Hospital, Hanoi, Vietnam.
Jazyk:	angličtina
Zdroj:	Asia Pacific journal of clinical nutrition [Asia Pac J Clin Nutr] 2017 Jan; Vol. 26 (1), pp. 49-58.
DOI:	10.6133/apjcn.122015.02
Abstrakt:	Background and Objectives: To determine the nutritional status of patients with esophageal cancer, and to investigate its relationship with performance status and prognosis. Methods and Study Design: This clinical, cross-sectional study was conducted from August 2014 to February 2015 at National Cancer Hospital, Hanoi, Vietnam. Stage III/IV esophageal cancer patients were assessed for their nutritional status (patient-generated subjective global assessment (PG-SGA) and SGA scores, BMI, mid-arm circumference (MAC), energy and protein intakes, weight changes, Karnofsky and Eastern cooperative oncology group performance scores (KPS/ECOG), and Glasgow prognostic score (GPS). Results: Sixty-four male patients were enrolled. The mean ± standard deviation of PG-SGA score was 9.88±4.41. SGA revealed 44% as class B and 6.2% as class C. The BMI revealed 43.8% of patients were underweight. MAC measurement revealed 29.7% of undernourished patients. Patients with an energy intake <25 kcal/kg/d comprised 54.7%, and 48.4% with <1 g/kg/day of protein. Totally, 68.8%, 84.4% and 92.2% patients exhibited weight loss past 2-weeks, one-month and six-months, respectively. The PG-SGA and SGA strongly correlated with the KPS (r=-0.717 and 0.632, both p<0.001) and ECOG (r=0.672 and 0.626, both p<0.001), but were weakly correlated with the GPS (r=0.332 and 0.278, p<0.01 and 0.05). The KPS, ECOG, BMI, MAC, energy and protein intakes, and weight change were not correlated with the GPS. Conclusions: Malnutrition, weight change, and insufficient intake were noteworthy in esophageal cancer patients. The PG-SGA and SGA were strongly correlated with the performance status, but weakly correlated with prognostic indices.
Databáze:	MEDLINE
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