Using Respondent Driven Sampling to Identify Malaria Risks and Occupational Networks among Migrant Workers in Ranong, Thailand.

Autor: Wangroongsarb P; Bureau of Vector Borne Diseases, Department of Disease Control, Ministry of Public Health, Nonathaburi, Thailand., Hwang J; U.S. President's Malaria Initiative, Malaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America.; Global Health Group, University of California San Francisco, California, United States of America., Thwing J; Malaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America., Karuchit S; Thailand MOPH-US CDC Collaboration, Nonathaburi, Thailand., Kumpetch S; Ranong Provincial Health Office, Ministry of Public Health, Ranong, Thailand., Rand A; Department of Infectious & Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., Drakeley C; Department of Infectious & Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom., MacArthur JR; Thailand MOPH-US CDC Collaboration, Nonathaburi, Thailand., Kachur SP; Malaria Branch, Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, Georgia, United States of America., Satimai W; Bureau of Vector Borne Diseases, Department of Disease Control, Ministry of Public Health, Nonathaburi, Thailand., Meek S; Malaria Consortium, London, United Kingdom., Sintasath DM; U.S. President's Malaria Initiative, USAID/RDMA, Bangkok, Thailand.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2016 Dec 29; Vol. 11 (12), pp. e0168371. Date of Electronic Publication: 2016 Dec 29 (Print Publication: 2016).
DOI: 10.1371/journal.pone.0168371
Abstrakt: Background: Ranong Province in southern Thailand is one of the primary entry points for migrants entering Thailand from Myanmar, and borders Kawthaung Township in Myanmar where artemisinin resistance in malaria parasites has been detected. Areas of high population movement could increase the risk of spread of artemisinin resistance in this region and beyond.
Methods: A respondent-driven sampling (RDS) methodology was used to compare migrant populations coming from Myanmar in urban (Site 1) vs. rural (Site 2) settings in Ranong, Thailand. The RDS methodology collected information on knowledge, attitudes, and practices for malaria, travel and occupational histories, as well as social network size and structure. Individuals enrolled were screened for malaria by microscopy, Real Time-PCR, and serology.
Results: A total of 619 participants were recruited in Ranong City and 623 participants in Kraburi, a rural sub-district. By PCR, a total of 14 (1.1%) samples were positive (2 P. falciparum in Site 1; 10 P. vivax, 1 Pf, and 1 P. malariae in Site 2). PCR analysis demonstrated an overall weighted prevalence of 0.5% (95% CI, 0-1.3%) in the urban site and 1.0% (95% CI, 0.5-1.7%) in the rural site for all parasite species. PCR positivity did not correlate with serological positivity; however, as expected there was a strong association between antibody prevalence and both age and exposure. Access to long-lasting insecticidal treated nets remains low despite relatively high reported traditional net use among these populations.
Conclusions: The low malaria prevalence, relatively smaller networks among migrants in rural settings, and limited frequency of travel to and from other areas of malaria transmission in Myanmar, suggest that the risk for the spread of artemisinin resistance from this area may be limited in these networks currently but may have implications for regional malaria elimination efforts.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
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