Hyperglycemia during the immediate period following liver transplantation.
Autor: | Werner KT; Division of Gastroenterology & Hepatology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA; Division of Gastroenterology & Hepatology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA., Mackey PA; Division of Endocrinology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA; Division of Endocrinology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA., Castro JC; Information Technology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA; Information Technology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA., Carey EJ; Division of Gastroenterology & Hepatology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA; Division of Gastroenterology & Hepatology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA., Chakkera HA; Division of Nephrology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA; Division of Nephrology, Mayo Clinic Hospital, Phoenix, AZ 85054, USA., Cook CB; Division of Endocrinology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA; Division of Preventive, Occupational & Aerospace Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA; Division of Endocrinology, Mayo Clinic, 13400 East Shea Boulevard, Scottsdale, AZ 85259, USA; Division of Preventive, Occupational & Aerospace Medicine, Mayo Clinic, Scottsdale, AZ 85259, USA. |
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Jazyk: | angličtina |
Zdroj: | Future science OA [Future Sci OA] 2016 Jan 27; Vol. 2 (1), pp. FSO97. Date of Electronic Publication: 2016 Jan 27 (Print Publication: 2016). |
DOI: | 10.4155/fsoa-2015-0010 |
Abstrakt: | Aim: High blood glucose levels in the hospital are common among transplant recipients. Methods: Retrospective analysis, stratified by diagnosis of pretransplant diabetes mellitus (DM). Results: Of 346 patients, 96 had pretransplant DM (insulin, n = 60; no insulin, n = 36) and 250 did not. Patients with pretransplant DM had higher inpatient mean glucose levels and more hyperglycemia and hypoglycemia (all p < 0.01). For patients without pretransplant DM, the need for insulin at discharge increased 23% for every 5-year age increase (odds ratio: 1.23; 95% CI: 1.06-1.44; p = 0.007) and 51% for every five units of glucose measurements >180 mg/dl (OR: 1.51; 95% CI: 1.23-1.95; p < 0.01). Conclusion: Inpatient hyperglycemia was common in liver transplant recipients. Hospital practitioners must anticipate the need to teach self-management skills to liver transplant recipients. Competing Interests: Financial & competing interests disclosure The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties. No writing assistance was utilized in the production of this manuscript. |
Databáze: | MEDLINE |
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