Factors contributing to delays in diagnosis of breast cancers in Ghana, West Africa.

Autor: Brinton L; National Cancer Institute, 9609 Medical Center Drive, Room 7E-442, MSC 9776, Bethesda, MD, 20892-9776, USA. brintonl@mail.nih.gov., Figueroa J; National Cancer Institute, 9609 Medical Center Drive, Room 7E-442, MSC 9776, Bethesda, MD, 20892-9776, USA.; University of Edinburgh, Edinburgh, Scotland, UK., Adjei E; Komfo Anoyke Teaching Hospital, Kumasi, Ghana., Ansong D; Komfo Anoyke Teaching Hospital, Kumasi, Ghana., Biritwum R; University of Ghana, Accra, Ghana., Edusei L; Korle Bu Teaching Hospital, Accra, Ghana., Nyarko KM; University of Ghana, Accra, Ghana., Wiafe S; Peace and Love Hospital, Kumasi, Ghana., Yarney J; Korle Bu Teaching Hospital, Accra, Ghana., Addai BW; Peace and Love Hospital, Kumasi, Ghana., Awuah B; Komfo Anoyke Teaching Hospital, Kumasi, Ghana., Clegg-Lamptey JN; University of Ghana, Accra, Ghana.; Korle Bu Teaching Hospital, Accra, Ghana.
Jazyk: angličtina
Zdroj: Breast cancer research and treatment [Breast Cancer Res Treat] 2017 Feb; Vol. 162 (1), pp. 105-114. Date of Electronic Publication: 2016 Dec 26.
DOI: 10.1007/s10549-016-4088-1
Abstrakt: Background: Late diagnoses and poor prognoses of breast cancer are common throughout Africa.
Methods: To identify responsible factors, we utilized data from a population-based case-control study involving 1184 women with breast malignancies conducted in three hospitals in Accra and Kumasi, Ghana. Interviews focused on potential breast cancer risk factors as well as factors that might contribute to presentation delays. We calculated odds ratios (OR) and 95% confidence intervals (CI) comparing malignances with biopsy masses larger than 5 cm. (62.4% of the 1027 cases with measurable lesions) to smaller lesions.
Results: In multivariate analyses, strong predictors of larger masses were limited education (OR 1.96, 95% CI 1.32-2.90 Conclusions: Our findings suggest that additional communication, particularly among less educated women, could promote earlier breast cancer diagnoses. Involvement of individuals other than medical practitioners, including traditional healers, may be helpful in this process.
Competing Interests: This study was supported by the intramural research program of the National Cancer Institute (NCI). The authors declare that they have no conflict of interest.
Databáze: MEDLINE
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