Inter- and intraobserver agreement in computed tomography enterography in inflammatory bowel disease.

Autor:	Horvat N; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil., Tavares CC; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil., Andrade AR; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil., Cabral JC; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil., Leao-Filho HM; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil., Caiado AH; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil., Ueda SK; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil., Leite AZ; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil., Sipahi AM; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil., Rocha MS; Natally Horvat, Camila Carlos Tavares, Hilton Muniz Leao-Filho, Angela Hissae Motoyama Caiado, Serli Kiyomi Nakao Ueda, Manoel Souza Rocha, Radiology Department, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, SP 05403-010, Brazil.
Jazyk:	angličtina
Zdroj:	World journal of gastroenterology [World J Gastroenterol] 2016 Dec 07; Vol. 22 (45), pp. 10002-10008.
DOI:	10.3748/wjg.v22.i45.10002
Abstrakt:	Aim: To evaluate intra- and interobserver agreement in imaging features in inflammatory bowel disease and comparison with fecal calprotectin (FC) levels. Methods: Our institutional computed tomography enterography (CTE) database was retrospectively queried to identify patients who underwent CTE from January 2014 to June 2015. Patient inclusion criteria were confirmed inflammatory bowel disease (IBD) and FC collected < 4 mo after CTE without any change in clinical treatment or surgical treatment during this interval. The exclusion criterion was poor image quality. Two blinded abdominal radiologists, with 12 and 3 years of experience analyzed the CTE regarding localization (small bowel, colonic, both, or no disease detected); type of IBD (inflammatory, stenosing, fistulizing, > 1 pattern, or normal); and signs of active disease (present or absent). In 42 of 44 patients evaluated, routine CTE reports were made by one of the readers who re-evaluated the CTEs ≥ 6 mo later, to determine the intraobserver agreement. FC was considered a sign of disease activity when it was higher than 250 μg/g. Results: Forty-four patients with IBD (38 with Crohn's disease and 6 with ulcerative colitis) were included. There was a moderate interobserver agreement regarding localization of IBD (κ = 0.540), type of disease (κ = 0.410) and the presence of active signs in CTE (κ = 0.419). There was almost perfect intraobserver agreement regarding localization, type and signs of active disease in IBD. The κ values were 0.902, 0.937 and 0.830, respectively. After a consensus between both radiologists regarding inflammatory activity in CTE, we found that 24 (85.7%) of 28 patients who were classified with active disease had elevated FC, and six (37.5%) of 16 patients without inflammatory activity in CTE had elevated FC ( P = 0.003). The correlation between elevated FC and the presence of active disease in CTE was significant (κ = 0.495, P = 0.001). Conclusion: We found almost perfect intraobserver and moderate interobserver agreement in the signs of active disease in CTE with concurrence of high FC levels. Competing Interests: Conflict-of-interest statement: We have no financial relationships to disclose.
Databáze:	MEDLINE
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