Magnetic resonance imaging based functional imaging in paediatric oncology.

Autor: Manias KA; Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK; Department of Paediatric Oncology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. Electronic address: karenphotiou@doctors.org.uk., Gill SK; Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK; Department of Paediatric Oncology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. Electronic address: S.K.Gill.1@bham.ac.uk., MacPherson L; Department of Radiology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. Electronic address: Lesley.Macpherson@bch.nhs.uk., Foster K; Department of Radiology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. Electronic address: Katharine.Foster@bch.nhs.uk., Oates A; Department of Radiology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. Electronic address: Adam.Oates@bch.nhs.uk., Peet AC; Institute of Cancer and Genomic Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK; Department of Paediatric Oncology, Birmingham Children's Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK. Electronic address: a.peet@bham.ac.uk.
Jazyk: angličtina
Zdroj: European journal of cancer (Oxford, England : 1990) [Eur J Cancer] 2017 Feb; Vol. 72, pp. 251-265. Date of Electronic Publication: 2016 Dec 21.
DOI: 10.1016/j.ejca.2016.10.037
Abstrakt: Imaging is central to management of solid tumours in children. Conventional magnetic resonance imaging (MRI) is the standard imaging modality for tumours of the central nervous system (CNS) and limbs and is increasingly used in the abdomen. It provides excellent structural detail, but imparts limited information about tumour type, aggressiveness, metastatic potential or early treatment response. MRI based functional imaging techniques, such as magnetic resonance spectroscopy, diffusion and perfusion weighted imaging, probe tissue properties to provide clinically important information about metabolites, structure and blood flow. This review describes the role of and evidence behind these functional imaging techniques in paediatric oncology and implications for integrating them into routine clinical practice.
(Copyright © 2016 Elsevier Ltd. All rights reserved.)
Databáze: MEDLINE
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