Mosquito Behavior Change After Distribution of Bednets Results in Decreased Protection Against Malaria Exposure.

Autor:	Thomsen EK; Liverpool School of Tropical Medicine, United Kingdom., Koimbu G; Papua New Guinea Institute of Medical Research, Vector Borne Diseases Unit, Madang, 511, Madang, Papua New Guinea., Pulford J; Liverpool School of Tropical Medicine, United Kingdom., Jamea-Maiasa S; Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea, Ura Y; Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea, Keven JB; Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, MI, USA., Siba PM; Papua New Guinea Institute of Medical Research, Goroka, Papua New Guinea, Mueller I; Walter and Eliza Hall Institute, Parkville, Victoria, Australia., Hetzel MW; Swiss Tropical and Public Health Institute, Basel, Switzerland.; University of Basel, Switzerland., Reimer LJ; Liverpool School of Tropical Medicine, United Kingdom.
Jazyk:	angličtina
Zdroj:	The Journal of infectious diseases [J Infect Dis] 2017 Mar 01; Vol. 215 (5), pp. 790-797.
DOI:	10.1093/infdis/jiw615
Abstrakt:	Background: Behavioral resilience in mosquitoes poses a significant challenge to mosquito control. Although behavior changes in anopheline vectors have been reported over the last decade, there are no empirical data to suggest they compromise the efficacy of vector control in reducing malaria transmission. Methods: In this study, we quantified human exposure to both bites and infective bites of a major malaria vector in Papua New Guinea over the course of 4 years surrounding nationwide bednet distribution. We also quantified malaria infection prevalence in the human population during the same time period. Results: We observed a shift in mosquito biting to earlier hours of the evening, before individuals are indoors and protected by bednets, followed by a return to preintervention biting rates. As a result, net users and non-net users experienced higher levels of transmission than before the intervention. The personal protection provided by a bednet decreased over the study period and was lowest in the adult population, who may be an important reservoir for transmission. Malaria prevalence decreased in only 1 of 3 study villages after the distribution. Discussion: This study highlights the necessity of validating and deploying vector control measures targeting outdoor exposure to control and eliminate malaria. (© The Author 2016. Published by Oxford University Press for the Infectious Diseases Society of America.)
Databáze:	MEDLINE
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