Pharmacologic management of pain in patients with Chikungunya: a guideline.

Autor: Brito CA; Departamento de Medicina Clínica, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., Sohsten AK; Instituto de Tratamento da Dor, Real Hospital Português de Beneficência em Pernambuco, Recife, Pernambuco, Brazil., Leitão CC; Departamento de Medicina Clínica, Universidade Federal de Pernambuco, Recife, Pernambuco, Brazil., Brito RC; Departamento de Pediatria, Universidade de Pernambuco, Recife, Pernambuco, Brazil., Valadares LD; Departamento de Reumatologia, Hospital Agamenom Magalhães, Recife, Pernambuco, Brazil., Fonte CA; Departamento de Reumatologia, Hospital Getúlio Vargas, Recife, Pernambuco, Brazil., Mesquita ZB; Departamento de Pediatria, Instituto de Medicina Integral Professor Fernando Figueira, Recife, Pernambuco, Brazil., Cunha RV; Departamento de Infectologia, Universidade Federal de Mato Grosso do Sul, Campo grande, Mato Groso do Sul, Brazil.; Fundação Oswaldo Cruz, Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil., Luz K; Departamento de Infectologia, Universidade Federal do Rio Grande do Norte, Natal, Rio Grande do Norte, Brazil., Leão HM; Escola Superior de Ética e Bioética, Conselho Regional de Medicina de Pernambuco, Recife, Pernambuco, Brazil., Brito CM; Curso de Graduação em Medicina, Universidade de Pernambuco, Recife, Pernambuco, Brazil., Frutuoso LC; Programa Nacional de Controle da Dengue, Ministério da Saúde, Brasília, Brazil.
Jazyk: angličtina
Zdroj: Revista da Sociedade Brasileira de Medicina Tropical [Rev Soc Bras Med Trop] 2016 Nov-Dec; Vol. 49 (6), pp. 668-679.
DOI: 10.1590/0037-8682-0279-2016
Abstrakt: From the arrival of Chikungunya virus in the Americas in 2013 until March 2016, approximately two million cases of the disease have been reported. In Brazil, the virus was identified in 2014 and thousands of people have been affected. The disease has high attack rates, infecting 50% of a population within a few months. Approximately 50% of infected people develop chronic symptoms lasting for months or years. Joint involvement is the main clinical manifestation of Chikungunya. It is characterized by swelling and intense pain that is poorly responsive to analgesics, both in the acute and chronic phase of the disease. This significantly compromises quality of life and may have immeasurable psychosocial and economic repercussions, constituting therefore, a serious public health problem requiring a targeted approach. Physicians are often not familiar with how to approach the management of pain, frequently prescribing limited analgesics, such as dipyrone, in sub-therapeutic doses. In addition, there are few published studies or guidelines on the approach to the treatment of pain in patients with Chikungunya. Some groups of specialists from different fields have thus developed a protocol for the pharmacologic treatment of Chikungunya-associated acute and chronic joint pain; this will be presented in this review.
Databáze: MEDLINE