Simple prediction model for unfavorable outcome in ischemic stroke after intravenous thrombolytic therapy.

Autor:	Amitrano D; Hospital Copa D´Or, Unidade de Cuidado Neurointensivo, Rio de Janeiro RJ, Brasil.; Universidade Federal Fluminense, Departamento de Neurologia, Rio de Janeiro RJ, Brasil., Silva IR; Universidade Federal Fluminense, Departamento de Neurologia, Rio de Janeiro RJ, Brasil.; Unidade Neurointensiva, Americas Medical Center, Rio de Janeiro, Brazil., Liberato BB; Hospital Copa D´Or, Unidade de Cuidado Neurointensivo, Rio de Janeiro RJ, Brasil.; Unidade Neurointensiva, Americas Medical Center, Rio de Janeiro, Brazil., Batistella V; Hospital Copa D´Or, Unidade de Cuidado Neurointensivo, Rio de Janeiro RJ, Brasil., Oliveira J; Hospital Copa D´Or, Unidade de Cuidado Neurointensivo, Rio de Janeiro RJ, Brasil., Nascimento OJ; Universidade Federal Fluminense, Departamento de Neurologia, Rio de Janeiro RJ, Brasil.
Jazyk:	angličtina
Zdroj:	Arquivos de neuro-psiquiatria [Arq Neuropsiquiatr] 2016 Dec; Vol. 74 (12), pp. 986-989.
DOI:	10.1590/0004-282X20160152
Abstrakt:	Objective: We aimed to develop a model to predict unfavorable outcome in patients with acute ischemic stroke treated with intravenous thrombolytic therapy (IVT), based on simple variables present on admission. Methods: Retrospective analysis of acute ischemic stroke patients treated with IVT in a hospital in Rio de Janeiro. Clinical and radiographic variables were selected for analysis. Multivariate logistic regression was used to develop a predictive model. Results: We analyzed a total of 82 patients. Median National Institutes of Health Stroke Scale (NIHSS) on admission was 9 (3-22), 40.2% presented with a hyperdense artery sign (HAS), 62% had identifiable early parenchymal changes and 61.6% experienced a favorable outcome. An NIHSS score of > 12 on arrival, age > 70 and the presence of HAS were associated with the outcome, even after correction in a logistic regression model. Conclusion: An NIHSS > 12 on arrival, presence of HAS and age > 70 years were predictors of unfavorable outcome at three months in patients with acute ischemic stroke treated with IVT.
Databáze:	MEDLINE
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