An independent, landmark-dominated head-direction signal in dysgranular retrosplenial cortex.

Autor: Jacob PY; Institute of Behavioural Neuroscience, Research Department of Experimental Psychology, Division of Psychology and Language Sciences, University College London, London, UK., Casali G; Institute of Behavioural Neuroscience, Research Department of Experimental Psychology, Division of Psychology and Language Sciences, University College London, London, UK., Spieser L; Department of Psychology, City University of London, London, UK., Page H; Institute of Behavioural Neuroscience, Research Department of Experimental Psychology, Division of Psychology and Language Sciences, University College London, London, UK., Overington D; Institute of Behavioural Neuroscience, Research Department of Experimental Psychology, Division of Psychology and Language Sciences, University College London, London, UK., Jeffery K; Institute of Behavioural Neuroscience, Research Department of Experimental Psychology, Division of Psychology and Language Sciences, University College London, London, UK.
Jazyk: angličtina
Zdroj: Nature neuroscience [Nat Neurosci] 2017 Feb; Vol. 20 (2), pp. 173-175. Date of Electronic Publication: 2016 Dec 19.
DOI: 10.1038/nn.4465
Abstrakt: We investigated how landmarks influence the brain's computation of head direction and found that in a bidirectionally symmetrical environment, some neurons in dysgranular retrosplenial cortex showed bidirectional firing patterns. This indicates dominance of neural activity by local environmental cues even when these conflicted with the global head direction signal. It suggests a mechanism for associating landmarks to or dissociating them from the head direction signal, according to their directional stability and/or utility.
Competing Interests: KJ is a non-shareholding director of Axona Ltd
Databáze: MEDLINE
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