Kidney volume and ambulatory blood pressure in children.

Autor:	Gurusinghe S; Division of Pediatric Nephrology, Department of Pediatrics, Cohen Children's Medical Center of New York, New Hyde Park, NY, USA., Palvanov A; Department of Radiology, Northwell Health, New Hyde Park, NY, USA., Bittman ME; Division of Pediatric Radiology, NYU Langone Medical Center, New York, NY, USA., Singer P; Division of Pediatric Nephrology, Department of Pediatrics, Cohen Children's Medical Center of New York, New Hyde Park, NY, USA., Frank R; Division of Pediatric Nephrology, Department of Pediatrics, Cohen Children's Medical Center of New York, New Hyde Park, NY, USA., Chorny N; Division of Pediatric Nephrology, Department of Pediatrics, Cohen Children's Medical Center of New York, New Hyde Park, NY, USA., Infante L; Division of Pediatric Nephrology, Department of Pediatrics, Cohen Children's Medical Center of New York, New Hyde Park, NY, USA., Sethna CB; Division of Pediatric Nephrology, Department of Pediatrics, Cohen Children's Medical Center of New York, New Hyde Park, NY, USA.
Jazyk:	angličtina
Zdroj:	Journal of clinical hypertension (Greenwich, Conn.) [J Clin Hypertens (Greenwich)] 2017 May; Vol. 19 (5), pp. 498-503. Date of Electronic Publication: 2016 Dec 16.
DOI:	10.1111/jch.12954
Abstrakt:	Low nephron number has been shown to be a risk factor for hypertension (HTN) in adulthood. Kidney volume may serve as a surrogate marker for nephron mass. The relationship between kidney volume and ambulatory blood pressure (BP) in the pediatric population is not known. A retrospective chart review of children younger than 21 years who were evaluated for HTN was performed. Twenty-four-hour BP and ultrasonography data were obtained. Multiple regression was used to examine associations between BP and kidney volume. Of 84 children (mean age 13.87 years, 72.6% males), 54 had HTN. Systolic BP index during the awake, sleep, and 24-hour periods (all P≤.05) was found to be positively correlated with total kidney volume. Greater total kidney volume was found to be a positive predictor of 24-hour and sleep systolic index (P≤.05). It failed to serve as a predictor of HTN, pre-HTN, or white-coat HTN. Contrary to expectation, total kidney volume was positively associated with systolic BP indices. (©2016 Wiley Periodicals, Inc.)
Databáze:	MEDLINE
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